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MetabolomicsThe patatin-like protein PlpD forms novel structurally dynamic homodimers in the Pseudomonas aeruginosa outer membrane

Members of the Omp85 superfamily of outer membrane proteins (OMPs) found in Gram-negative bacteria, mitochondria and chloroplasts are characterized by a distinctive 16-stranded β-barrel transmembrane domain and at least one periplasmic POTRA domain. All previously studied Omp85 proteins promote c...

2025-12-08 | MTBLS9803 | MetaboLights
ProteomicsA proteomic study on the membrane protein fraction of T cells confirms high substrate selectivity for the ER translocation inhibitor cyclotriazadisulfonamide
Cyclotriazadisulfonamide (CADA) inhibits the co-translational translocation of type I integral membrane protein human CD4 (huCD4) across the ER in a signal peptide (SP)-dependent way. Previously, sortilin was identified as a secondary substrate for CADA but showed reduced CADA sensitivity as compare...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD027712 | Pride
Cd4  cyclotriazadisulfonamide (cada)  er co-translational translocation  signal peptide  silac 
UnknownCrystallographic snapshot of cellulose synthesis and membrane translocation.
Not available
S-EPMC3542415 | biostudies-literature
ProteomicsDegP Chaperone supression of toxic inner membrane translocation intermediates
Dataset accompanying manuscript DegP Chaperone supression of toxic inner membrane translocation intermediates in PlosOne RAW files from 6 separate E coli proteomes (LC/MS/MS) analyzed by LFQ in DegP WT and null sequences with induced or uninduced pertactin expression at two separate time points afte...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2016-08-25 | MSV000080095 | MassIVE
GenomicsEndocytosed dsRNAs induce lysosomal membrane permeabilization that allows cytosolic dsRNA translocation for Drosophila RNAi response
Endocytosed dsRNAs induce lysosomal membrane permeabilization that allows cytosolic dsRNA translocation for Drosophila RNAi response
PRJNA1023479 | ENA
UnknownObserving cellulose biosynthesis and membrane translocation in crystallo.
Not available
S-EPMC4843519 | biostudies-literature
ProteomicsMolecular snapshots of translation and protein translocation at the ER membrane
The dynamic ribosome-translocon complex, which resides at the endoplasmic reticulum (ER) membrane, produces a major fraction of the human proteome . It governs the synthesis, translocation, membrane insertion, N-glycosylation, folding and disulfide-bond formation of nascent proteins. While individua...
ORGANISM(S): Homo sapiens (Human) 
2023-02-03 | PXD035475 | Pride
Ribosome Er membrane Elongation factor 1 
ProteomicsFine-tuning regulation of (p)ppGpp-driven outer membrane vesicle formation in Acinetobacter baumannii
While the roles of (p)ppGpp on cytosolic proteins are well established, its effects on membrane remodeling remain elusive. The translocation of signal recognition particle (SRP)-dependent proteins can be regulated by binding (p)ppGpp to two key GTPase components: FtsY, which interacts with SecYEG, a...
ORGANISM(S): Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377) 
2025-03-15 | PXD057710 | Pride
Membrane remodeling Membrane disruption Acinetobacter baumannii Outer membrane vesicle Stringent response (p)ppgpp 
GenomicsPD-L1 ubiquitination by MIB2 enables its translocation to the plasma membrane for tumor immune evasion
PD-L1 ubiquitination by MIB2 enables its translocation to the plasma membrane for tumor immune evasion
PRJNA906110 | ENA
UnknownMembrane translocation of folded proteins.
Not available
S-EPMC9251779 | biostudies-literature
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