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MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
ProteomicsDistinct Secretomes and Proteomes of Vibrio cholerae isolates indued by Sublethal Concentrations of Heavy Metals Cd2+, Ni2+, Pb2+, and Zn2+ Stresses
Vibrio cholerae is a Gram-negative bacterium that can cause pandemic cholera in humans. Meanwhile, the aquaculture environment heavy metal pollution situation is serious. In this study, the growths of the V. cholerae isolates recovered from commonly consumed fish were measured for the first time in ...
ORGANISM(S): Vibrio Cholerae H1 Vibrio Cholerae 
2023-10-12 | PXD046079 |
ProteomicsProtective mechanisms of heparin against AGEs-induced endothelial injury
Advanced glycation end products (AGEs) in diabetes can cause endothelial damage. Heparin, widely known as a recognized anticoagulant, is also a multifunctional therapeutic drug. This study investigated whether heparin could ameliorate AGEs-induced endothelial injury. Remarkably, heparin effectively ...
ORGANISM(S): Homo Sapiens 
2025-01-19 | PXD056219 |
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