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TranscriptomicsTLR4 ligands LPS and MPLA differentially regualte effector and memory CD8 T cell differentiation
Here we implemented a simple dendritic cell (DC)-mediated immunization approach to study the effects of commonly used adjuvants, Toll like receptor (TLR) ligands, on effector CD8 T cell differentiation and memory T cell development. To our surprise, we found that the TLR4 ligand LPS was far more sup...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-50764 | biostudies-arrayexpress
TranscriptomicsGene expression data from Wild Type and Nlrp10 deficient dendritic cells treated with or without LPS
Nlrp10-deficient mice have a profound defect in helper T cell-driven immune responses. T cell priming is impaired due to a defect in the emigration of a dendritic cells from inflamed tissue and antigen transport to draining lymph nodes. DC chemotaxis to CCR7-dependent and independent ligands is inta...
ORGANISM(S): Mus musculus 
2012-02-23 | E-GEOD-36009 | biostudies-arrayexpress
UnknownTgSWO from Trichoderma guizhouense NJAU4742 promotes growth in cucumber plants by modifying the root morphology and the cell wall architecture.
Not available
S-EPMC6721366 | biostudies-literature
UnknownRNA interference-mediated silencing of genes involved in the immune responses of the soybean pod borer Leguminivora glycinivorella (Lepidoptera: Olethreutidae).
Not available
S-EPMC6003399 | biostudies-literature
TranscriptomicsProfiling livers from LPS-treated rats
This program addresses the gene signature associated with LPS-treated liver in rat. Specifically, which genes are differentially expressed in livers of the Sprague Dawley rats treated with LPS? The LPS-treated liver profiling data was analyzed by identifying genes that were up- and down-regulated at...
ORGANISM(S): Rattus norvegicus 
2013-03-22 | E-GEOD-38078 | biostudies-arrayexpress
TranscriptomicsCircadian patterns of gene expression in the human brain and disruption in major depressive disorder
A cardinal symptom of Major Depressive Disorder (MDD) is the disruption of circadian patterns. Yet, to date, there is no direct evidence of circadian clock dysregulation in the brains of MDD patients. Circadian rhythmicity of gene expression has been observed in animals and peripheral human tissues,...
ORGANISM(S): Homo sapiens 
2013-04-20 | E-GEOD-45642 | biostudies-arrayexpress
UnknownHousekeeping gene dysregulation in psoriasis: integrative multi-cohort and single-cell analysis reveals keratinocyte-centric molecular mechanisms and diagnostic biomarkers.
Not available
S-EPMC12433973 | biostudies-literature
UnknownSIRT4-Mediated Deacetylation of PRDX3 Attenuates Liver Ischemia Reperfusion Injury by Suppressing Ferroptosis.
Not available
S-EPMC12320503 | biostudies-literature
UnknownIntegration of zinc anode and cement: unlocking scalable energy storage.
Not available
S-EPMC11444079 | biostudies-literature
UnknownCYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6.
Not available
S-EPMC4220159 | biostudies-literature
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