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ProteomicsTargeting LRBA triggers CTLA4 degradation and antitumor immunity for cancer immunotherapy
The lipopolysaccharide-responsive beige-like anchor protein (LRBA) deficiency causes severe autoimmune diseases and cytotoxic T-lymphocyte-associated protein 4 (CTLA4) loss in humans. However, the impact of LRBA on antitumor immunity remains understudied. Here, we identified the role of LRBA in anti...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-23 | PXD064363 | Pride
ProteomicsSpatial distribution of the proteome in human body and cancers
The ddaPASEF and diaPASEF data were acquired from over 60 types of human specimens. Based on these, the consensus spectral libraries were generated and used in subsequent DIA analysis to demonstrate a quantitative human proteome map and discover potential cancer biomarkers.
ORGANISM(S): Homo Sapiens 
2026-04-15 | PXD077178 |
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