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Transcriptional profiling of MEPs purified from wild type and Bmi1-/- mice. Two-condition experiment, WT vs. Bmi1-/- MEPs. Biological replicates: 3 WT replicates, 3 Bmi1-/- replicates.
ORGANISM(S): Mus musculus 
Transgene insertion in proximity to the c-Myb gene disrupts c-Myb expression in megakaryocyte-erythrocyte progenitors (MEPs), resulting in skewed commitment to megakaryocyte lineage. To understand the genes regulated by c-Myb at the megakaryocyte-erythrocyte bifurcation, MEPs of c-MybTG/c-MybTG mic...
ORGANISM(S): Mus musculus 
Transcriptional profiling of MEPs purified from wild type and Bmi1-/- mice.
ORGANISM(S): Mus musculus 
2014-11-18 | GSE63411 | GEO
bulkRNA-seq LSKs CMPs MEPs GMPs from bone marrow and spleen
Comparison of bone marrow or splenic originated stem cell populations (LSKs, CMPs, MEPs, and GMPs) in a mouse model of emergency granulopoieis.
ORGANISM(S): Mus musculus 
2026-04-17 | GSE314281 | GEO
Effects of Vhl deletion in Dmp1-expressing cells alterering gene expression of megakaryocyte-erythroid progenitor cells (MEPs)
Murine Myeloid-Erythroid Progenitors (MEPs): WT vs. Bmi1-/-
Comparison of mRNA expression profiles of MEPs with or without mutations in JAK2 and Ezh2 by RNA sequencing. MEPs mRNA was extracted from six different transgenic mice (SclCre, SclCre;Ezh2+/-, SclCre;Ezh2-/-, SclCre; JAK2V617F, SclCre; JAK2V617F;Ezh2+/-, SclCre; JAK2V617F;Ezh2-/-) 10 weeks after tam...
ORGANISM(S): Mus musculus 
CB CD34+ cells were isolated by Miltenyi miniMACS column. Cells were prestimulated in HPGM with 100 ng/ml KITL, FLT#L and TPO for 48 hrs. Cells were transduced with control MiNR1 or STAT5A-ER in three rounds over 48 hrs. Hematopoietic stem cells (HSCs), common myeloid progenitors (CMPs), granulocyte...
ORGANISM(S): Homo sapiens 
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