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Previous studies have revealed that UV-stimulation of a variety of cells leads to activation of the EGF receptor, induction of Egr1, growth inhibition and apoptosis. On the other hand both Egr1 and EGF receptor activation are implicated in promoting the progression of prostate cancer. We treated M...
ORGANISM(S): Homo sapiens 
Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress
ORGANISM(S): Homo sapiens 
The purpose of the experiment is to identify mRNAs under differential translational control in Ki-ras transformed 267B1 cells as compared to the parental cell line. Total and polysome-associated mRNAs were isolated from exponentially growing cells and used to prepare biotin-labeled cRNA probes for ...
ORGANISM(S): Homo sapiens 
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