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GenomicsProgram specificity for Ptf1a in PancreasM-BM- versusM-BM- Neural Tube DevelopmentM-BM- correlates with distinctM-BM- collaborating cofactors and chromatin accessibility
Ptf1a is a lineage-specific basic-helix-loop-helix transcription factor critical in the development of both the pancreas and nervous system. How one transcription factor controls diverse programs of gene expression is a fundamental question in developmental biology. To uncover molecular strategies f...
ORGANISM(S): Mus musculus 
2013-08-15 | E-GEOD-47459 | biostudies-arrayexpress
TranscriptomicsTranscription Factor Network Specifying Inhibitory versus Excitatory Neurons in the Dorsal Spinal Cord [RNA-Seq]
The proper balance of excitatory and inhibitory neurons is crucial to normal processing of somatosensory information in the dorsal spinal cord. Two neural basic helix-loop-helix transcription factors, Ascl1 and Ptf1a, are essential for generating the correct number and sub-type of neurons in multipl...
ORGANISM(S): Mus musculus 
2014-06-13 | E-GEOD-55831 | biostudies-arrayexpress
GenomicsTranscription Factor Network Specifying Inhibitory versus Excitatory Neurons in the Dorsal Spinal Cord [ChIP-Seq]
The proper balance of excitatory and inhibitory neurons is crucial to normal processing of somatosensory information in the dorsal spinal cord. Two neural basic helix-loop-helix transcription factors, Ascl1 and Ptf1a, are essential for generating the correct number and sub-type of neurons in multipl...
ORGANISM(S): Mus musculus 
2014-06-13 | E-GEOD-55840 | biostudies-arrayexpress
UnknownPaediatric leukaemia DNA methylation profiling using MBD enrichment and SOLiD sequencing on archival bone marrow smears.
Not available
S-EPMC4364676 | biostudies-literature
UnknownPredominantly Persistent Intraretinal Fluid in the Comparison of Age-related Macular Degeneration Treatments Trials.
Not available
S-EPMC10282893 | biostudies-literature
UnknownEffects of medical therapies on retinopathy progression in type 2 diabetes.
Not available
S-EPMC4026164 | biostudies-literature
UnknownFine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease.
Not available
S-EPMC3036586 | biostudies-literature
UnknownWhole-genome sequencing reveals host factors underlying critical COVID-19.
Not available
S-EPMC9259496 | biostudies-literature
UnknownEffect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.
Not available
S-EPMC8491132 | biostudies-literature
UnknownMapping the human genetic architecture of COVID-19.
Not available
S-EPMC8674144 | biostudies-literature
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