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TranscriptomicsEvolutionary dynamics of gene and isoform regulation in mammalian tissues
Most mammalian genes produce multiple distinct mRNAs through alternative splicing, but the extent of splicing conservation is not clear.  To assess tissue-specific transcriptome variation across mammals, we sequenced cDNA from 9 tissues from 4 mammals and one bird in biological triplicate, at unprec...
ORGANISM(S): Mus musculus 
2012-12-21 | E-GEOD-41637 | biostudies-arrayexpress
TranscriptomicsStrand-specific RNA-seq of nine mouse tissues
This experiment is contains mouse organism part samples and strand-specific RNA-seq data from experiment E-GEOD-41637 (https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-41637/), which aimed at assessing tissue-specific transcriptome variation across mammals, with chicken used as an outgroup in e...
ORGANISM(S): Mus musculus 
2012-12-21 | E-MTAB-2801 | biostudies-arrayexpress
TranscriptomicsStrand-specific RNA-seq of nine rat tissues
This experiment is contains rat organism part samples and strand-specific RNA-seq data from experiment E-GEOD-41637 (https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-41637/), which aimed at assessing tissue-specific transcriptome variation across mammals, with chicken used as an outgroup in evo...
ORGANISM(S): Rattus norvegicus 
2012-12-21 | E-MTAB-2800 | biostudies-arrayexpress
TranscriptomicsStrand-specific RNA-seq of nine cow tissues
This experiment is contains cow organism part samples and strand-specific RNA-seq data from experiment E-GEOD-41637 (https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-41637/), which aimed at assessing tissue-specific transcriptome variation across mammals, with chicken used as an outgroup in evo...
ORGANISM(S): Bos taurus 
2012-12-21 | E-MTAB-2798 | biostudies-arrayexpress
TranscriptomicsStrand-specific RNA-seq of nine rhesus macaque tissues
This experiment is contains rhesus macaque organism part samples and strand-specific RNA-seq data from experiment E-GEOD-41637 (https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-41637/), which aimed at assessing tissue-specific transcriptome variation across mammals, with chicken used as an outg...
ORGANISM(S): Macaca mulatta 
2012-12-21 | E-MTAB-2799 | biostudies-arrayexpress
TranscriptomicsStrand-specific RNA-seq of nine chicken tissues
This experiment is contains chicken organism part samples and strand-specific RNA-seq data from experiment E-GEOD-41637 (https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-41637/), which aimed at assessing tissue-specific transcriptome variation across mammals, with chicken used as an outgroup in...
ORGANISM(S): Gallus gallus 
2012-12-21 | E-MTAB-2797 | biostudies-arrayexpress
TranscriptomicsWidespread regulated alternative splicing of single codons accelerates proteome evolution
Thousands of human genes contain introns ending in NAGNAG motifs (N any nucleotide), where both NAGs can function as 3' splice sites, yielding isoforms differing by inclusion/exclusion of just three bases. However, the functional importance of NAGNAG alternative splicing is highly controversial. Usi...
ORGANISM(S): Homo sapiens 
2012-01-05 | E-GEOD-30017 | biostudies-arrayexpress
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