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Increasing studies associating glycerophospholipids with various pathological conditions highlight the need for their thorough characterization. However, the intricate composition of the lipidome due to the presence of lipid isomers poses significant challenges to structural lipidomics. This stud...

2023-10-10 | MTBLS8547 | MetaboLights

Desalination brine discharge poses emerging threats to benthic marine organisms through combined salinity stress and metal contamination. This study investigated the individual and combined effects of salinity (35 ppt) and metal exposure (Cu, Fe, and Cd) on the sea cucumber Apostichopus japonicus...

2026-03-18 | MTBLS14079 | MetaboLights

Based on a unique pathogen iron interplay mechanism, this work establishes a new therapeutic paradigm targeting iron homeostasis at the host-pathogen interface via sequential metabolic priming, offering a broadly applicable strategy to reprogram resource asymmetry and combat fungal infection.

2026-05-10 | MTBLS13715 | MetaboLights
Background: The high number of heavy metal resistance genes in the soil bacterium Cupriavidus metallidurans CH34 makes it an interesting model organism to study microbial responses to heavy metals. Results: In this study the transcriptional response of this bacterium was measured after challenging i...
ORGANISM(S): Cupriavidus metallidurans CH34 
We have successfully bioinertized a nanoLC/MS/MS system for the highly sensitive analysis of phosphopeptides by depleting metal ions from the mobile phase. We found that not only the direct contact of phosphopeptides with metal materials, but also the indirect contact with HPLC pump through the mobi...
ORGANISM(S): Homo Sapiens (human) 
We used 2', 3'-cyclic phosphate cDNA synthesis and Illumina sequencing to identify and quantify metal-ion-independent endoribonuclease cleavage sites in host and viral RNAs. To make cDNA libraries, we exploited the 2’, 3’-cyclic phosphate at the end of RNA fragments produced by RNase L and other met...
ORGANISM(S): Homo sapiens 
Effect of mild metal ion - stress (500µM AlCl3, 500µM VCl3, 1.5mM ZnCl2) on cellular metabolism, resp. on transcription - 30min incubation in yeast Saccharomyces cerevisiae (JSwt - is a FY derivate; MATaleu2ura3trp1HIS3)
ORGANISM(S): Saccharomyces cerevisiae 
Effect of mild metal ion-stress (40µM AgNO3, 200µM AsCl3, 2µM CdCl2, 100µM CoCl2, 30µM HgCl2, 1.5mM MnCl2, 1.5mM NiSO4) on cellular metabolism, resp. on transcription - 30min incubation in yeast Saccharomyces cerevisiae
ORGANISM(S): Saccharomyces cerevisiae 
Fungal communities in Metal rusts Raw sequence reads
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