Metastatic driver

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Unknown (1153)
Genomics (428)
Transcriptomics (218)
Proteomics (37)
Other (13)
Genomic (5)
Methylation profiling (5)
Clinical (4)
Metabolomics (2)
Models (1)

Organisms

Homo sapiens (288)
Mus musculus (83)
Aerococcus urinae NBRC 15544 = CCUG 36881 (30)
Andropogon gerardi (30)
Bacteria (30)
Canis lupus familiaris (30)
Cnidaria (30)
Ectopseudomonas oleovorans CECT 5344 (30)
Ensifer adhaerens (30)
Enterococcus faecalis (30)
Globicatella sanguinis (30)
Halictus scabiosae (30)
Human immunodeficiency virus 1 (30)
Mesocricetus auratus (30)
Methylohalobius crimeensis 10Ki (30)
Miscanthus x giganteus (30)
Mus musculus (30)
Panicum virgatum (30)
Pseudomonas aeruginosa SJTD-1 (30)
Rabies virus Nishigahara RCEH (30)
Rattus norvegicus (30)
Rattus rattus (30)
Rhodococcus jostii RHA1 (30)
Rhodopseudomonas palustris (30)
Populus trichocarpa x Populus deltoides (2)
Vigna unguiculata (1)
Cryptococcus bacillisporus (1)
Rattus norvegicus (1)
Drosophila melanogaster (1)
Mus (1)

Organisms

Homo sapiens (180)
Mus musculus (69)
Homo (1)
Mus (1)
Drosophila melanogaster (1)

Repository

ENA (295)
geo (228)
EGA (80)
biostudies-arrayexpress (61)
pride (30)
dbGaP (5)
MassIVE (4)
iProX (2)
MetaboLights (2)
BioModels (1)
jPOST (1)

Tissue

Cell culture (8)
Epithelial cell (6)
Melanocyte (5)
Skin (3)
Colon (2)
Malignant cell (2)
Prostate gland (2)
Brain (1)
Breast cancer cell (1)
Fibroblast (1)
Keratinocyte (1)
Liver (1)
Lung (1)
Mammary gland tumor cell (1)
Monocyte (1)
Pancreatic ductal carcinoma cell (1)
Skin of body (1)
Testis (1)
Urine (1)
Uvea (1)

Disease

Melanoma (7)
Prostate cancer (4)
Prostate adenocarcinoma (3)
Colorectal Neoplasms (2)
Breast cancer (2)
Colon cancer (2)
Sarcoma (1)
Colorectal cancer (1)
Fibrolamellar carcinoma (1)
Head and neck squamous cell carcinoma (1)
Malignant neoplasm of ovary (1)
Medulloblastoma (1)
Oral squamous cell carcinoma (1)
Pancreatic ductal adenocarcinoma (1)
Skin melanoma (1)
Tongue squamous cell carcinoma (1)
Uveal melanoma (1)

Technology Type

Mass Spectrometry (30)
Shotgun proteomics (18)
Affinity purification coupled with mass spectrometry proteomics (5)
Bottom-up proteomics (4)
Illumina HiSeq 2000 (3)
Illumina HiSeq 2500 (2)
Illumina Genome Analyzer II (2)
Data-dependent acquisition (2)
Illumina HiSeq 2500, Illumina HiSeq 4000, ILLUMINA, NextSeq 500 (1)
ILLUMINA, NextSeq 500 (1)
Affymetrix OncoScan FFPE Express (1)
Illumina HiSeq 2500, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina HiSeq 2500 (ILLUMINA) (1)
Ion Torrent Proton, Illumina MiSeq, NextSeq 550 (1)
Illumina HiSeq 2000, Illumina HiSeq 2500, ILLUMINA (1)
Illumina Genome Analyzer II, Illumina HiSeq 2000 (1)
Illumina MiSeq (1)
Mass spectrometry (1)
Mass spectrometry assay (1)
Data-independent acquisition (1)
Top-down proteomics (1)

Instrument Platform

Illumina HiSeq 2500 (2)
Q Exactive HF-X (2)
Illumina NovaSeq 6000 (1)
Orbitrap Fusion ETD (1)
Q Exactive Plus (1)
Gas Chromatography MS - positive (1)
Liquid Chromatography MS - positive - reverse-phase (1)
Liquid Chromatography MS - negative - reverse-phase (1)
Liquid Chromatography MS - positive - reverse phase (1)
Liquid Chromatography MS - negative - reverse phase (1)

Publication Date

2026 (73)
2025 (51)
2024 (32)
2023 (24)
2022 (21)
2015 (19)
2016 (17)
2021 (15)
2014 (14)
2010 (12)
2020 (10)
2013 (9)
2017 (8)
2011 (6)
2018 (6)
2012 (5)
2019 (4)
2007 (1)

CHEBI ID

CHEBI:172955 (1)
CHEBI:172954 (1)
CHEBI:172953 (1)
CHEBI:172952 (1)
CHEBI:172951 (1)
CHEBI:42758 (1)
CHEBI:24301 (1)
CHEBI:172950 (1)
CHEBI:47014 (1)
CHEBI:46983 (1)
CHEBI:38263 (1)
CHEBI:141293 (1)
CHEBI:141282 (1)
CHEBI:141281 (1)
CHEBI:141280 (1)
CHEBI:141279 (1)
CHEBI:141275 (1)
CHEBI:141274 (1)
CHEBI:141273 (1)
CHEBI:136488 (1)
CHEBI:136791 (1)
CHEBI:136788 (1)
CHEBI:71732 (1)
CHEBI:134271 (1)
CHEBI:71722 (1)
CHEBI:155835 (1)
CHEBI:155834 (1)
CHEBI:66853 (1)
CHEBI:67058 (1)
CHEBI:139297 (1)

Metabolite Name

Cyanidin conjugate (A9) (1)
Cyanidin conjugate (A5) (1)
Quercetin-3-Glu (1)
Kaempferol 3,7-O-dirhamnopyranoside (1)
Isorhamnetin-3-Glu-7-Rha (1)
Quercetin-3,7-O-a-L-dirhamnopyranoside (1)
Kaempferol-3-O-b-glucopyranosyl-7-O-a-rhamnopyranoside (1)
Cyanidin conjugate (A11) (1)
Kaempferol-diHex-Rha (1)
Quercetin-3-O-b-glucopyranosyl-7-O-a-rhamnopyranoside (1)
Cyanidin conjugate (A10) (1)
Quercetin-Hex-diRha (1)
Kaempferol-3-Rha-7-Glu (1)
Quercetin-diHex-Rha (1)
Kaempferol-3-O-a-L-rhamnopyranosyl(1,2)-b-D-glucopyranoside-7-O-a-L-rhamnopyranoside (1)
Quercetin-3-O-a-L-rhamnopyranosyl(1,2)-b-D-glucopyranoside-7-O-a-L-rhamnopyranoside (1)

IsPrivate

False (1)

First Public Date

2026 (69)
2025 (58)
2023 (33)
2024 (31)
2021 (20)
2022 (16)
2016 (12)
2014 (11)
2019 (10)
2017 (10)
2015 (9)
2018 (8)
2020 (7)
2011 (1)

Modelling Approach

Boolean model (1)

Study status

Recruiting (2)
Not yet recruiting (2)

Study type

Transcription profiling by array (25)
RNA-seq of coding RNA (10)
Comparative genomic hybridization by array (9)
ChIP-seq (4)
Methylation profiling by array (4)
Genotyping by array (3)
Methylation profiling by high throughput sequencing (2)
Interventional (2)
Unknown experiment type (1)
Transcription profiling by tiling array (1)
Transcription profiling by RT-PCR (1)
MicroRNA profiling by high throughput sequencing (1)
Observational patient registry (1)
Observational (1)

Release Date

2022 (158)
2021 (156)
2025 (147)
2023 (142)
2024 (114)
2020 (99)
2019 (69)
2018 (60)
2016 (58)
2017 (52)
2015 (49)
2014 (33)
2026 (22)
2013 (20)
2012 (13)
2010 (13)
2011 (7)
2007 (1)

Lab affiliation

Moffitt Cancer Center Tampa, FL, USA (3)
Department of Chemistry and Biochemistry. University of Colorado, Boulder. Boulder, CO 80303 (2)
1Department of Urology, Emory University School of Medicine, Atlanta, GA, USA (1)
Associate Professor, Department of biotechnology and research, Sir Ganga ram hospital, New Delhi -110060, Delhi, India (1)
CECAD Research Center, University of Cologne, Joseph-Stelzmann-Str 26, 50931 Cologne, Germany (1)
CRUK - Beatson Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (1)
Canary Center at Stanford for Cancer Early Detection Department of Radiology Stanford University School of Medicine (1)
Center for Biomedical Mass Spectrometry Boston University School of Medicine 670 Albany St, Rm 511 Boston, MA 02118-2646 USA (1)
Chair of Proteomics and Bioanalytics Technical University of Munich Germany (1)
Department of Biochemistry, Schulich School of Medicine and Dentistry, Western University, London, ON, N6A 5C1, Canada (1)
Department of Oncology-Pathology, Karolinska Institutitet (1)
Department of Translational Medicine, Lund University, Sweden (1)
Department of Urology, Emory University School of Medicine, Atlanta, GA, USA (1)
Division of Clinical Protein Science & Imaging, Department of Clinical Sciences (Lund), Department of Biomedical Engineering, Lund University, Lund, Sweden (1)
Head Proteomics Group, Leiden University Medical Center, Center for Proteomics and Metabolomics, PO Box 9600, Postal zone P1-Q, 2300 RC Leiden, The Netherlands (1)
OmicScouts GmbH (1)
Professor of Chemistry University of California Riverside Riverside, CA 92521-0403 (1)
Proteomics Core Facility, University of Gothenburg, Sweden (1)
Proteomics Facility, The Netherlands Cancer Institute, Amsterdam, The Netherlands (1)
Proteomics Platform CIC bioGUNE Bizkaia Tech. Park Build. 800 Derio 48160 Spain (1)
Reader in Centre for Genomics and Computational Biology Barts Cancer Institute Queen Mary, University of London John Vane Science Centre, Charterhouse Square, London EC1M 6BQ Tel: +44 (0)20 7882 8266 | Fax: +44 (0)20 7882 3891 | Email: p.cutillas@qmul.ac.uk www.bci.qmul.ac.uk/research/centre-profiles/haemato-oncology.html https://www.bci.qmul.ac.uk/en/staff/item/pedro-cutillas (1)
School of Biosciences University of Sheffield Sheffield, S10 2TN United Kingdom (1)
Section for Translational Surgical Oncology and Biobanking, Department of Surgery, University of Lübeck and University Hospital Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538 Lübeck Germany (1)
St. Jude Children's Research Hospital Memphis, TN 38105 (1)
University of Minnesota, Twin-Cities, Pharmacology Department (1)
University of Minnesota, Twin-cities Pharmacology Department (1)
University of Siena (1)

Location

China (2)
Italy (1)
United States (1)

Keyword

Second-line (1)
RAS-mutant (1)
Fruquintinib plus Chemotherapy (1)
RAS mutation (1)

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NFIB is a driver of SCLC initiation, progression and metastasis in mouse and marks metastatic disease in patients

Small Cell Lung Cancer (SCLC) is the most aggressive type of lung cancer with early metastatic dissemination and invariable development of resistant disease for which no effective treatment is available to date. Mouse models of SCLC based on inactivation of Rb1 and Trp53 developed earlier showed fre...

ORGANISM(S): Mus musculus

2016-07-29 | E-GEOD-82005 | biostudies-arrayexpress

Dynamics and transcriptomic driver landscape of metastatic osteosarcoma

PRJNA588395 | ENA

Analysis of paired primary and metastatic cell lines identifies common DNA methylation changes in melanoma metastasis.

Using 1 melanocyte and 6 melanoma cell line (3 pair of primary and metastatic), we generated base-resolution DNA methylation maps to document DNA methylation drivers of melanoma metastasis. Here we generated single-nucleotide resoultion DNA methylation map of a total of 7 cell lines using Reduced Re...

ORGANISM(S): Homo sapiens

2017-05-17 | E-GEOD-70621 | biostudies-arrayexpress

Metastatic site influences driver gene function in pancreatic cancer [scMultiome]

PRJNA1030031 | ENA

Metastatic site influences driver gene function in pancreatic cancer [scRNA-seq]

PRJNA1262412 | ENA

Metastatic site influences driver gene function in pancreatic cancer [ATAC-seq]

PRJNA1030029 | ENA

Metastatic site influences driver gene function in pancreatic cancer [RNA-seq]

PRJNA1030030 | ENA

Metastatic site influences driver gene function in pancreatic cancer [[InVitro ATAC-Seq]]

PRJNA1275804 | ENA

Metastatic site influences driver gene function in pancreatic cancer [InVitro RNA-Seq]

PRJNA1275802 | ENA

Clonal Architectures and Driver Mutations in Metastatic Melanomas

This study contains sequence data from 15 patients with stage IV melanoma, including the whole genome sequence of 15 metastatic tumors and corresponding normal blood samples from 13 cases, and targeted capture sequence of four synchronous metastatic samples from two additional cases. These data p...

phs001241 | dbGaP

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1866 Results

Show results for

Organisms

Organisms

Repository

Tissue

Disease

Technology Type

Instrument Platform

Publication Date

CHEBI ID

Metabolite Name

IsPrivate

First Public Date

Modelling Approach

Study status

Study type

Release Date

Lab affiliation

Location

Keyword

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