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ProteomicsResolving oxidative damage to methionine by an unexpected membrane-associated stereoselective reductase discovered using chiral fluorescent probes
Non-enzymatic oxidative processes in living organisms are one of the inevitable consequences of respiration and environmental conditions. They can lead to the formation of two stereoisomers (R and S) of methionine sulfoxide, and the redox balance between methionine and methionine sulfoxide in protei...
ORGANISM(S): Escherichia coli 
2019-06-12 | PXD013610 | Pride
E.coli Oxidative damage Methionine sulfoxide 
UnknownMethionine sulfoxide reductase A is a stereospecific methionine oxidase.
Not available
S-EPMC3127874 | biostudies-literature
ProteomicsDoes protein-bound methionine sulfoxide provides a proteomic basis for ageing in beech seeds?
Beech trees produce seeds irregularly, necessitating the storage of these seeds for forestation. Despite the acquisition of desiccation tolerance during development, beech seeds lose viability during long-term storage faster than orthodox-type seeds. Seeds stored for short (3 years) and long (20 yea...
ORGANISM(S): Fagus sylvatica 
2024-05-23 | PXD046531 | Pride
Longevity Methionine sulfoxide reductase Oxidative stress Fagus sylvatica Seed storage 
TranscriptomicsA stemness-related ZEB1-MSRB3 axis governs cellular pliancy and cancer genome stability.
Genomic instability is a prominent driver of tumorigenesis. However, a significant fraction of human cancers display few genomic aberrations, suggesting alternative roads towards malignancy. Here, we show that the differentiation status of normal human mammary epithelial cells influences the early r...
ORGANISM(S): Homo sapiens 
2017-03-23 | E-MTAB-4145 | biostudies-arrayexpress
UnknownMethionine sulfoxide reductase contributes to meeting dietary methionine requirements.
Not available
S-EPMC3358449 | biostudies-literature
GenomicsMycobacterium smegmatis secreting methionine sulfoxide reductase A (MsrA) modulates cellular processes in mouse macrophages
Mycobacterium smegmatis secreting methionine sulfoxide reductase A (MsrA) modulates cellular processes in mouse macrophages
PRJNA874679 | ENA
ProteomicsBacillus cereus msrABmsrA double mutant strain proteomics under fermentative anoxic conditions, exoproteome
This project provides tandem mass spectrometry datasets of Bacillus cereus ATCC 14579 wild-type strain without its pBClin15 plasmid devoided of both the methionine sulfoxide reductase AB (msrAB)and methionine sulfoxide reductase A (msrA) genes. The double mutant strain was grown under fermentative a...
ORGANISM(S): Bacillus cereus (strain ATCC 14579 / DSM 31) 
2021-09-10 | PXD024848 | Pride
Proteomics Methionine sulfoxide reductase Anaerobiosis Exoproteome Bacillus cereus 
ProteomicsBacillus cereus msrABmsrA double mutant strain proteomics under fermentative anoxic conditions, cellular proteome
This project provides tandem mass spectrometry datasets of Bacillus cereus ATCC 14579 wild-type strain without its pBClin15 plasmid devoided of both the methionine sulfoxide reductase AB (msrAB)and the methionine sulfoxide reductase A (msrA) genes. The double mutant strain was grown under fermentati...
ORGANISM(S): Bacillus cereus (strain ATCC 14579 / DSM 31) 
2021-09-10 | PXD024849 | Pride
Cellular proteome Atcc 14579 Proteomics Methionine sulfoxide reductase Anaerobiosis Bacillus cereus 
UnknownMammals reduce methionine-S-sulfoxide with MsrA and are unable to reduce methionine-R-sulfoxide, and this function can be restored with a yeast reductase.
Not available
S-EPMC2568918 | biostudies-literature
UnknownCharacterization and solution structure of mouse myristoylated methionine sulfoxide reductase A.
Not available
S-EPMC3408158 | biostudies-literature
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