Sort   by:  
 Page size 
MetabolomicsRemote solid cancers rewire hepatic nitrogen metabolism via host nicotinamide-N-methyltransferase
Not available
ORGANISM(S): Mus musculus 
ST002163 | MetabolomicsWorkbench
MetabolomicsRemote solid cancers rewire hepatic nitrogen metabolism via host nicotinamide-N-methyltransferase (AML cells)
Not available
ORGANISM(S): Mus musculus 
ST002167 | MetabolomicsWorkbench
GenomicsCpG underrepresentation and the new bacterial CpG specific DNA methyltransferase M.MpeI
The CpG depleted Mycoplasma penetrans harbors a CpG specific C5 methyltransferase. The aim of this experiment was to confirm the specificity of the methyltransferase in vivo and in vitro. Genomic DNA from Mycoplasma penetrans and Escherichia coli genomic DNA that either was or was not methylated in ...
ORGANISM(S): Escherichia coli 
2012-11-29 | E-GEOD-41022 | biostudies-arrayexpress
ProteomicsRPL40 methyltransferase discovery and characterisation
The eukaryotic ribosome is highly modified by protein methylation, yet many of the responsible methyltransferases remain unknown. Here we have identified SMYD5 as a ribosomal protein methyltransferase that catalyses trimethylation of RPL40 at lysine 22. Through a systematic mass spectrometry-based a...
ORGANISM(S): Homo Sapiens 
PXD056489 | panorama
ProteomicsMT-MAMS: protein methyltransferase motif analysis by mass spectrometry
Protein methyltransferases can recognise their substrates through linear sequence motifs and determination of these motifs is critical to understand methyltransferase mechanism, function and drug targeting. Here we describe MT-MAMS (methyltransferase motif analysis by mass spectrometry), a quantitat...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2018-09-03 | PXD009515 | Pride
Motif Methylation Methyltransferase 
ProteomicsAged Mouse Muscle: Sedentary or Exercised Animals with or without Nicotinamide N-methyltransferase Inhibitor Treatment
Aged (22-mo) female mice (n=35), obtained from the US NIH National Institute on Aging (NIA) Aged Rodent Colony, were randomly assigned to one of four groups: saline-treated sedentary ( n=9), nicotinamide N-methyltransferase inhibitor (NNMTi)-treated sedentary (10 mg/kg body weight; n=9), saline-trea...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-05-07 | MSV000094700 | MassIVE
ProteomicsThe METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates metabolism and development via translation (Identification of m1A mRNA methyltransferase in nucleus by TMT11-LC-MS/MS)
m1A has long been known to be important in tRNA and rRNA, but we recently mapped many m1A sites in mRNA as well. m1A is found on the 5’ ends of genes, usually around the first splice site, but we have yet to understand how it effects transcript fate. Identifying the methyltransferase would be a ma...
ORGANISM(S): Homo sapiens (Human) 
2021-11-30 | PXD028832 | Pride
Mettl5 Mass spectrometry Proteomics M1a mrna methyltransferase Trmt112 
TranscriptomicsSmall RNA mediated DNA (cytosine-5) methyltransferase 1 inhibition leads to aberrant DNA methylation
Mammalian cells contain copious amounts of RNA including both coding and non-coding RNA (ncRNA). Generally the ncRNAs function to regulate gene expression at the transcriptional and post-transcriptional level. Among ncRNA, the long ncRNA and small ncRNA can affect histone modification, DNA methylati...
ORGANISM(S): Homo sapiens 
2015-04-21 | E-GEOD-68027 | biostudies-arrayexpress
TranscriptomicsThe Wilms' tumour 1 transcription factor regulates epigenetic states via DNA methyltransferase 3A
The Wilms' tumour 1 transcription factor regulates epigenetic states via DNA methyltransferase 3A. The data consists of two Nimblegen promoter/CpG island microarrays hybridized with MCIP DNA immunoprecipitated from either a HEK293-derived cell line expressing a heterologous WT1 cDNA (W210) or a cont...
ORGANISM(S): Homo sapiens 
2012-11-05 | E-GEOD-39713 | biostudies-arrayexpress
TranscriptomicsImmune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers [methylation]
Epigenetic therapy is emerging as a potential therapy for solid tumors. To investigate its mechanism of action, we performed integrative expression and methylation analysis of 63 cancer cell lines (breast, colorectal, and ovarian) after treatment with the DNA methyltransferase inhibitor 5-azacitidin...
ORGANISM(S): Homo sapiens 
2014-05-08 | E-GEOD-57342 | biostudies-arrayexpress
Sort   by:  
 Page size