Sort   by:  
 Page size 
TranscriptomicsCD8+/CD103+ tumor-infiltrating lymphocytes are tumor-specific tissue-resident memory T cells and a prognostic factor for survival in lung cancer patients
We had previously demonstrated the role of CD103 integrin on lung tumor-infiltrating lymphocyte (TIL) clones in promoting specific TCR-mediated epithelial tumor cell cytotoxicity. However, the contribution of CD103 on intratumoral T-cell distribution and functions, and the prognosis significance of ...
ORGANISM(S): Homo sapiens 
2015-06-29 | E-MTAB-3266 | biostudies-arrayexpress
TranscriptomicsP24_STVI_colorectal_cancer_MIR
Focal and temporal tumor heterogeneity can represent a major challenge for biology-guided therapies. This study proposes to investigative molecular discrepancies between primary colorectal cancer samples and matched metastases
ORGANISM(S): Homo sapiens 
2014-12-30 | E-MTAB-2868 | biostudies-arrayexpress
TranscriptomicsP24_STVI_colorectal_cancer_GEX
Focal and temporal tumor heterogeneity can represent a major challenge for biology-guided therapies. This study proposes to investigative molecular discrepancies between primary colorectal cancer samples and matched metastases
ORGANISM(S): Homo sapiens 
2014-12-30 | E-MTAB-2864 | biostudies-arrayexpress
TranscriptomicsIGR_CamaraClayette_MCL
We designed a gene profiling experiment to identify genes involved in secondary drug resistance in mantle cell lymphomas (MCL). We obtained paired tissue samples collected before treatment and after relapse or progression. Variations in gene expression between the 2 samples were estimated for 5 pati...
ORGANISM(S): Homo sapiens 
2013-01-17 | E-MTAB-1090 | biostudies-arrayexpress
TranscriptomicsIGR_Raslova_LMMC
Characterization of genetic alterations in monocoyte lineage (CD14+ cells) of two CMML (Chronicle Myelo-Monocytic Leukemia) patients. Previously we have shown that RUNX1 downregulates MYH10 expression in megacaryocyte lineage leading in MYH10 overexpression in platelets of patients wiht RUNX1 geneti...
ORGANISM(S): Homo sapiens 
2013-01-16 | E-MTAB-1121 | biostudies-arrayexpress
TranscriptomicsIGR_Raslova_IPS
FPD/AML is a constitutional disorder characterized by germline abnormalities in the hematopoietic transcription factor RUNX1, also called AML1. Mouse models have revealed the essential role of Runx1 during the first steps of hematopoiesis with an embryonic lethality and a complete absence of definit...
ORGANISM(S): Homo sapiens 
2014-01-19 | E-MTAB-1526 | biostudies-arrayexpress
TranscriptomicseIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies
The amounts of eIF4G and eIF4B were decreased in the vemurafenib-treated sensitive A375 cell line. To find mechanisms behind this decrease, we sought to identify the genes whose expression changes after vemurafenib treatment in A375 cells as compared to Mel624 cells by using microarrays.
ORGANISM(S): Homo sapiens 
2014-12-30 | E-MTAB-2607 | biostudies-arrayexpress
GenomicsChIP-Seq of H3K4me3 in primary unstimulated monocyte subsets from 2 healthy donors buffy coats
Identification of H3K4me3 localization on chromatin in primary unstimulated monocyte subsets
ORGANISM(S): Homo sapiens 
2018-11-09 | E-MTAB-7290 | biostudies-arrayexpress
TranscriptomicsIGR_Itzykson_CMML
Genomic studies in chronic myeloid malignancies, including myeloproliferative neoplasms (MPN), myelodysplastic syndromes (MDS) and MPN/MDS, have identified common mutations in genes encoding signaling, epigenetic, transcription and splicing factors. Analysis of 18 of these genes in a cohort of 224 c...
ORGANISM(S): Homo sapiens 
2013-01-17 | E-MTAB-1044 | biostudies-arrayexpress
Sort   by:  
 Page size