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TranscriptomicsGene Expression Profiles in Early Stages Uterine Serous Carcinomas in comparison to G3 and G1 Endometrioid Adenocarcinoma
The goal of this study was to identify differentially expressed genes (DEG) between uterine serouscarcinoma (USC) vs. early stages high/low grade endometrioid adenocarcinoma (EAC). Gene expression profiles of 33 cancer samples were analyzed (EAC-G1=11, EAC-G3=11, USC-G3=11) using the human genome wi...
ORGANISM(S): Homo sapiens 
2011-03-31 | E-GEOD-24537 | biostudies-arrayexpress
TranscriptomicsMicroarray Analysis Reveals Distinct Gene Expression Profiles Among Different Tumor Histology, Stage and Disease Outcomes in Endometrial Adenocarcinoma
The goal of this study was to identify differentially expressed genes (DEG) between early vs. late stage endometrioid adenocarcinoma (EAC) and uterine serous carcinoma (USC), as well as between disease outcomes in each of the two histological subtypes. Gene expression profiles of 20 cancer samples w...
ORGANISM(S): Homo sapiens 
2010-11-17 | E-GEOD-23518 | biostudies-arrayexpress
GenomicsBreast Cancer Suppressor Role of RUNX1: Estrogen-dependent Regulation of AXIN1 and b-catenin
The transcription factor RUNX1 exhibits recurrent loss-of-function mutations in estrogen receptor-positive (ER+) breast cancer (BCa). Its knockdown in vitro decreased AXIN1 expression in estrogen-dependent manner. Consistently, RUNX1 and AXIN1 mRNA levels are strongly correlated in ER+, not ER- tu...
ORGANISM(S): Homo sapiens 
2016-02-22 | E-GEOD-65313 | biostudies-arrayexpress
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