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Heterosis is a fundamental biological phenomenon characterized by the superior performance of a hybrid over its parents in many traits, but the underlying molecular basis remains elusive. To investigate whether DNA methylation plays a role in heterosis, we compared at single base-pair resolution th...
ORGANISM(S): Arabidopsis thaliana 
We evaluated changes in mRNA stability and transcription using 4sU metabolic pulse labeling across a four hour time course following activation of Jurkat T cells with PMA and PHA Measurement of total mRNA (T) and 4sU labeled mRNA (IP) in three biological replicates at five time points: prior to acti...
ORGANISM(S): Homo sapiens 
We investigated the impact of both BMP9 deficiency and replenishment on the pathogenesis of MI in mice. Our results showed an aggravated pathological phenotype of MI in BMP9 knockout (KO) mice, which can be alleviated by replenishment of BMP9. Therefore, we further investigated the mechanism whereby...
ORGANISM(S): Mus Musculus 
2024-04-17 | PXD051517 |
Male Sprague-Dawley rats were randomly divided into (1) mock surgery (MS) group, mock surgery after EP (EPMS) group, myocardial ischemia (MI) group and MI after EP (EPMI) group. Twenty-four hours after MI or mock surgery , left ventricular tissues below the ligation were collected for the iTRAQ prot...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-04-23 | PXD017765 | Pride
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