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MetabolomicsUntargeted metabolomics of offspring rats in MIA model

Maternal immune activation is a significant environmental factor for neurodevelopmental diseases. Although gut bacteria and their metabolites are linked to behavioral deficits in NDDs, the roles of gut fungi and secondary fungal metabolites remain unclear. Here, we induced MIA via a single intrap...

2026-01-20 | MTBLS12687 | MetaboLights
TranscriptomicsRNA expression analysis after Mia PaCa 2 cell treatment with demethylating agent 5-Aza-2’-deoxycitidine (5-Aza)
Transcriptional profiling of Mia PaCa 2 cells treated with 5-Aza for 96 h. Relative abundance to untreated control cells was used to estimate the effect of DNA demethylation on the expression of the RNAs. Two-condition experiment, 5-Aza-treated vs. untretated Mia PaCa 2 cells. Biological replicates:...
ORGANISM(S): Homo sapiens 
2015-06-30 | E-GEOD-62959 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression between MIA PaCa-2 cells transfected with miR-4653-3p mimic and negative control cells
To identify the target of miR-4653-3p, mRNA microarray analysis was performed to compare mRNA expression between MIA PaCa-2 cells transfected with miR-4653-3p mimic and negative control cells.
ORGANISM(S): Homo sapiens 
2023-05-28 | E-MTAB-11813 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Mia PaCa-2 cancer cells treated with a cell-permeable RAS inhibitor and its negative control
The action mechanism of a cell-permeable RAS inhibitor (Pen-cRaf-v1) and its binding-disrupting mutant (Pen-cRaf-v1-AA) was studied by transcription profiling of Mia PaCa-2 cancer cells treated with the inhibitors at the concentration of 10 microM for 3 hours.
ORGANISM(S): Homo sapiens 
2021-06-01 | E-MTAB-10403 | biostudies-arrayexpress
TranscriptomicsHuman lung minimally invasive adenocarcinoma (MIA): lepidic growth (LG) cancer cell pool vs. micro-invasion (MI) cancer cell pool
Transcriptional profiling of human lung minimally invasive adenocarcinoma cells comparing control lepidic growth (LG) cell pool with micro-invasion (MI) cell pool. Two-condition experiment, LG vs. MI cell pools. Biological replicates: 1 control LG cancer cell, 1 MI cancer cell in an individual MIA t...
ORGANISM(S): Homo sapiens 
2012-01-02 | E-GEOD-30663 | biostudies-arrayexpress
TranscriptomicsGenome wide analysis of pancreatic gene expression by Interleukin 1M-NM-2 in human epithelial pancreatic Mia Paca-2 cells.
Analysis of the pancreatic gene expression with IL-1M-NM-2 stimulation. Components of the integrin pathway were significantly altered with IL-1M-NM-2 which play critical role in the execution of apoptosis.The results revealed several important cellular pathways and the biological processes of the ge...
ORGANISM(S): Homo sapiens 
2012-06-20 | E-GEOD-26702 | biostudies-arrayexpress
TranscriptomicsA GNAS mutation found in pancreatic intraductal papillary mucinous neoplasms induces drastic alterations of gene expression profiles with upregulation of mucin genes.
GNAS, a gene encoding G-protein stimulating alpha subunit, is frequently mutated in intraductal papillary mucinous neoplasms (IPMNs), which is an indolent and slow-growing pancreatic neoplasm that secretes abundant mucin. GNAS mutation is not observed in conventional ductal adenocarcinomas of the pa...
ORGANISM(S): Homo sapiens 
2014-02-04 | E-GEOD-53350 | biostudies-arrayexpress
GenomicsmRNA expression data from RalGAPβ-deficient human pancreatic ductal adenocarcinoma cells (MIA PaCa-2), MIA PaCa-2 parental cells, and MIA PaCa-2 control cells
mRNA expression data from RalGAPβ-deficient human pancreatic ductal adenocarcinoma cells (MIA PaCa-2), MIA PaCa-2 parental cells, and MIA PaCa-2 control cells
PRJNA925906 | ENA
ProteomicsShedding lights on the alamandine signaling in CHO-MrgD and human pancreatic carcinoma cells: an antiproliferative effect was unveiled
Antiproliferative effect of ang-(1-7) has been further described and detailed, assessing its possibility as a therapeutic cancer control agent. Other endogenous peptides in this system have been studied and characterized, such as alamandine, a heptapeptide very similar to ang-(1-7) in terms of amino...
ORGANISM(S): Homo sapiens (Human) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2022-06-07 | PXD018529 | Pride
Mia paca-2 Human Cho Alamandine treatment 
GenomicsHomo sapiens isolate:MIA Paca2 cell line
MIA PaCa-2 cell variant genomic sequences
PRJNA400337 | ENA
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