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Investigation of whole genome gene expression level changes in Plasmodium falciparum 3D7 delta-PfPuf2 mutant, compared to the wild-type strain 3D7. The mutation engineered into this strain render tanslational control. The mutants analyzed in this study are further described in Miao J, Li J, Fan Q, ...
ORGANISM(S): Plasmodium falciparum 3D7 
Histone post-translational modifications (PTMs) play an essential role in epigenetic gene regulation. The Plasmodium falciparum genome encodes canonical and variant histones and a collection of conserved enzymes for histone PTMs and chromatin remodeling. Herein, we characterized the P. falciparum hi...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2022-09-14 | PXD031817 | Pride
The histone acetyltransferase (HAT) GCN5-associated SAGA complex is evolutionarily conserved from yeast to human and functions as a general transcription co-activator in global gene regulation. To study GCN5 associated complex in human malaria parasite Plasmodium falciparum, PfGCN5 was tagged with P...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2021-08-06 | PXD023389 | Pride
This study identified Plasmodium falciparum DNA methyltransferase (DNMT)associated proteins in parasite cytosol and nucleus, including RNA binding proteins and AP2-domain containing proteins, indicating this protein is involved in RNA process and transctiptional regulation.
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2023-07-20 | PXD032860 | Pride
In this study, we identified an MYST-associated complex in P. falciparum, which contains 11 of 13 conserved NuA4 subunits based on their domain structures. Meanwhile, reciprocal pulldowns not only confirmed the NuA4-like complex but also identified an SWR1-like complex, a histone remodeling complex,...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2024-03-18 | PXD046547 | Pride
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