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With improved whole-cell isolation protocols, we performed single-cell RNA sequencing (scRNA-seq) and profiled the transcriptomes from adult non-human primate brain. We identified discriminative cell populations with canonical and novel markers. Cross-species projection demonstrated the evolutionary...
ORGANISM(S): Macaca fascicularis 
Temozolomide (TMZ) is the first-line chemotherapeutic drug for glioblastoma treatment. It can induce O6-methylguanine DNA lesions, lead to prolonged G2–M arrest and ultimately cell death. However, the molecular response involved in TMZ inhibiting tumor growth has not been fully elucidated. In this s...
ORGANISM(S): Rattus Norvegicus 
2019-05-09 | PXD013790 |
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