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MetabolomicsMetabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor (Untargeted urine UPLC-MS assay)
BACKGROUND: Epidemiological evidence suggests a link between pesticide exposure and the development of metabolic diseases. However, most experimental studies have evaluated the metabolic effects of pesticides using individual molecules, often at non relevant doses or in combination with other r...
2019-05-28 | MTBLS596 | MetaboLights
TranscriptomicsSynergistic activation by p38MAPK and glucocorticoid signaling mediates induction of M2-like tumor-associated macrophages expressing the novel CD20 homolog MS4A8A
Analysis of bone marrow derived macrophages (BMDM) incubated with dexamethasone&IL4 (Dexa+IL4), B16F1 tumor conditioned medium (cmB16), and B16F1 tumor conditioned medium supplemented with dexamethasone&IL4 (cmB16+dexa+IL4). Results allow detection of genes that require synergistic stimulation of tu...
ORGANISM(S): Mus musculus 
2011-01-03 | E-GEOD-25707 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of indole-3-acetic acid at physiological concentrations (IAA) treatment of Arabidopsis seedlings
To demonstrate the analysis of differential expression using CATMA v1 arrays, Arabidopsis seedlings were treated with indole-3-acetic acid at physiological concentrations. The seedlings were germinated in liquid medium, and treated with indole-3-acetic acid for 30, 120 or 240 minutes. Changes in exp...
ORGANISM(S): Arabidopsis thaliana 
2004-05-31 | E-MEXP-65 | biostudies-arrayexpress
UnknownPrevalence and Overlap of Potential Embolic Sources in Patients With Embolic Stroke of Undetermined Source.
Not available
S-EPMC6761628 | biostudies-literature
TranscriptomicsRNA-seq of Mycobacterium tuberculosis H37Rv treated with alpibectir or a combination of alpibectir and ethionamide against untreated controls
Alpibectir potentiates the activity of ethionamide and prothionamide, which are second-line antibiotics used for tuberculosis treatment. Both are prodrugs whose antibacterial activity depends on bioactivation by oxidases, including the Baeyer-Villiger monooxygenase MymA. Alpibectir binds the transcr...
ORGANISM(S): Mycobacterium tuberculosis 
2025-12-10 | E-MTAB-16253 | biostudies-arrayexpress
GenomicsPassive and active DNA methylation and the interplay with genetic variation in gene regulation
DNA methylation is an essential1 epigenetic mark whose role in gene regulation and its dependency on genomic sequence and environment are not yet fully understood2,3. In this study we provide novel insights into the mechanistic relationships between genetic variation, DNA methylation and transcripto...
EGAS00001000446 | EGA
TranscriptomicsTranscription profiling of Arabidopsis mutants (elo2, elo3, drl1-2 and ang4) vs the wild type Ler strain
Microarray transcript profiling and RNA interference are two new technologies crucial for large-scale gene function studies in multicellular eukaryotes. Both rely on sequence-specific hybridization between complementary nucleic acid strands, inciting us to create a collection of gene-specific sequen...
ORGANISM(S): Arabidopsis thaliana 
2004-05-07 | E-MEXP-30 | biostudies-arrayexpress
GenomicsGENCORD2_DNAmethylation - samples
GENCORD2 DNA methylation
EGAD00010000460 | EGA
Genomicsena-DATASET-GenCord2-27-05-2013-09:30:55:905-40 - samples
204 individuals were genotyped with the Illumina 2.5M Omni chip. Filtered genotypes were imputed into the 1000 genomes project European panel SNPs. Beagle R2 is indicated in VCF files for further filtering. See Materials and Methods in publication for details.
EGAD00001000428 | EGA
Genomicsena-DATASET-GenCord2-22-05-2013-15:33:28:221-28 - samples
GENCORD2 RNA-seq BAM files using BWA
EGAD00001000425 | EGA
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