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ProteomicsOn tissue Top down microproteomic bridged to MALDI MS Imaging reveal the molecular physiome of brain regions
Tissue Top-down microproteomic was performed on 3 brain regions. 156 references proteins from different cellular compartments were characterized. Moreover, 11 Alternative proteins issued from alternative open reading frames (AltORF) were identified and were relied to the brain regions and associated...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-11-14 | PXD005424 | Pride
Alternative proteins Top down micro-proteomics Maldi imaging 
ProteomicsOvarian serous cancer tumor microenvironment investigated by MALDI MSI associated to Top-down microproteomic: Evidence of a hidden proteome as novel potential target
Top-down tissue microproteomic was performed in order to investigate tumoral tissue microenvironment. 289 proteins with post-translational modifications have been isolated from biospies including Tumor, Borderline and healthy regions of serous ovarian cancers. Tumor tissue displays a majority of pro...
ORGANISM(S): Homo sapiens (Human) 
2017-06-23 | PXD005420 | Pride
Alternative proteins Top down micro-proteomics Maldi imaging 
MetabolomicsArsenic induces metabolome remodeling in mature human adipocytes
Human lifetime exposure to arsenic through drinking water, food supply or industrial pollution leads to its accumulation in many organs such as liver, kidneys, lungs or pancreas but also adipose tissue. Recently, population-based studies revealed the association between arsenic exposure and the deve...
2025-05-23 | MTBLS8808 | MetaboLights
Genomicsena-DATASET-GenCord2-22-05-2013-15:33:28:221-28 - samples
GENCORD2 RNA-seq BAM files using BWA
EGAD00001000425 | EGA
GenomicsGENCORD2_DNAmethylation - samples
GENCORD2 DNA methylation
EGAD00010000460 | EGA
Genomicsena-DATASET-GenCord2-27-05-2013-09:30:55:905-40 - samples
204 individuals were genotyped with the Illumina 2.5M Omni chip. Filtered genotypes were imputed into the 1000 genomes project European panel SNPs. Beagle R2 is indicated in VCF files for further filtering. See Materials and Methods in publication for details.
EGAD00001000428 | EGA
GenomicsPassive and active DNA methylation and the interplay with genetic variation in gene regulation
DNA methylation is an essential1 epigenetic mark whose role in gene regulation and its dependency on genomic sequence and environment are not yet fully understood2,3. In this study we provide novel insights into the mechanistic relationships between genetic variation, DNA methylation and transcripto...
EGAS00001000446 | EGA
ModelsChaouiya2013 - EGF and TNFalpha mediated signalling pathway
Chaouiya2013 - EGF and TNFalpha mediated signalling pathway This model is described in the article: SBML qualitative models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools. Chaouiya C, Bérenguier D...
2024-09-02 | BIOMD0000000562 | BioModels
UnknownSexual health needs of female sex workers in Cote d'Ivoire: a mixed-methods study to prepare the future implementation of pre-exposure prophylaxis (PrEP) for HIV prevention.
Not available
S-EPMC6955511 | biostudies-literature
ProteomicsHigh-throughput identification of repurposable neuroactive drugs with potent anti-glioblastoma activity
Glioblastoma, the most aggressive primary brain cancer, has dismal prognosis, yet systemic treatment is limited to DNA-alkylating chemotherapies. New therapeutic strategies may emerge from exploring neurodevelopmental and neurophysiological vulnerabilities of glioblastoma. To this end, we here syste...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000090357 | MassIVE
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