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GenomicsFunctional link between Rad2 and Mediator
In this study, we generate genomic maps of Mediator, Rad2, Pol II, TBP and TFIIH, by ChIP coupled to next generation sequencing technology (ChIP-seq), in wild type strains from Saccharomyces cerevisiae. A related study involving ChIP-chip analysis of Rad2 occupany is also deposited at ArrayExpress ...
ORGANISM(S): Saccharomyces cerevisiae 
2013-12-01 | E-MTAB-1595 | biostudies-arrayexpress
GenomicsGenomic binding of Pol III transcription machinery and relationship with TFIIS distribution in mouse embryonic stem cells
RNA polymerase (RNA Pol) III synthesizes the tRNAs, the 5S ribosomal RNA and a small number of untranslated RNAs. In vitro, it also transcribes short interspersed nuclear elements (SINEs). We investigated the distribution of RNA Pol III and its associated transcription factors on the genome of mouse...
ORGANISM(S): Mus musculus 
2011-09-16 | E-MTAB-767 | biostudies-arrayexpress
ProteomicsInternalization of therapeutic antibodies into Dendritic cells as a risk factor for immunogenicity
The appended raw files, csv files and other documents were deposited into the public domain in support for the publication "Internalization of therapeutic antibodies into Dendritic cells as a risk factor for immunogenicity" by Michel Siegel, Anna-Lena Bolender, Axel Ducret, Johannes Fraidling, Katha...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-26 | MSV000095695 | MassIVE
ProteomicsDevelopment and qualification of a dendritic cell internalization assay contributing to the immunogenicity risk evaluation of biotherapeutics
The appended raw files, csv files and other documents were deposited into the public domain in support for the publication "Development and characterization of a dendritic cell internalization assay contributing to the immunogenicity risk evaluation of biotherapeutics" by Michel Siegel, Aman Padamse...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-12 | MSV000095578 | MassIVE
GenomicsFunctional link between TFIIB and Mediator
In this study, we generate genomic maps of Mediator, Pol II, TBP, TFIIH, TFIIA, TFIIB, TFIIE, TFIIF, by ChIP coupled to next generation sequencing technology (ChIP-seq), in wild type strains from Saccharomyces cerevisiae and in a mutant for the Mediator essential subunit Med10
ORGANISM(S): Saccharomyces cerevisiae 
2017-01-24 | E-MTAB-4607 | biostudies-arrayexpress
TranscriptomicsA new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion
The identification of subtype-specific translocations has revolutionized diagnostics of sarcoma and provided new insight into oncogenesis. We used RNA-Seq to investigate samples diagnosed as small round cell tumors of bone, possibly Ewing sarcoma, but lacking the canonical EWSR1-ETS translocation. A...
ORGANISM(S): Homo sapiens 
2012-03-03 | E-GEOD-34800 | biostudies-arrayexpress
ProteomicsAntibiofilm and antivirulence properties of 6-polyaminosteroid derivatives against antibiotic-resistant bacteria
The emergence of multi-drug resistant pathogens is a major public health problem, leading to rethink and innovate in our bacterial control strategies. Here, we explore the anti-biofilm and anti-virulence activities of nineteen 6-polyaminosterol derivatives (squalamine-based), presenting a modulation...
ORGANISM(S): Staphylococcus Aureus 
2023-12-20 | PXD048020 |
TranscriptomicsRad2 ChIP-chip experiment
This aim of this experiment is to assess the genome-wide Rad2 occupancy in yeast Saccharomyces cerevisiae by ChIP-chip, in the absence of exogenous genotoxic stress. A related study involving ChIP-seq analysis of Rad2 occupany is also deposited at ArrayExpress under accession number E-MTAB-1595 ( ww...
ORGANISM(S): Saccharomyces cerevisiae 
2013-12-01 | E-MEXP-3875 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human enterocytes cultured with different dietary lipids
The present study aimed to identify the specific impact of dietary lipids-containing micelles on gene expression in enterocytes.
ORGANISM(S): Homo sapiens 
2008-08-27 | E-MEXP-1446 | biostudies-arrayexpress
Genomicsena-DATASET-UNIGE-AL-25-11-2014-11:00:41:737-1967 - samples
Description not provided
EGAD00001001084 | EGA
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