Sort   by:  
 Page size 
ProteomicsIGDQ motogenic peptide gradient induces directional cell migration through integrin (αv)β3 activation in metastatic breast cancer
In the context of breast cancer metastasis study, we have shown in an in vitro model of cell migration that IGDQ-exposing (IsoLeu-Gly-Asp-Glutamine type I Fibronectin motif) monolayers (SAMs) on gold sustain the adhesion of MDA-MB-231 cells by triggering Focal Adhesion Kinase by activating integrins...
ORGANISM(S): Homo sapiens (Human) 
2022-11-08 | PXD024540 | Pride
Breast cancer  tnbc  cell migration  motogenic igdq motif  fibronectin type i  integrin alpha 5  integrin beta 3 
TranscriptomicsRNA-seq of human head and neck cancer cell line SQD9 knock-out for TMEM45A exposed to cisplatin
Human head and neck squamous cell carcinoma, SQD9 cells, were stable invalidated for TMEM45A using shRNA (Sigma). Then, transduced SQD9 cells were treated with 100 µM of cisplatin during 24h. All conditions were compared to untreated cells transduced with shRNA control (shCTL)(Sigma).
ORGANISM(S): Homo sapiens 
2020-03-04 | E-MTAB-7518 | biostudies-arrayexpress
TranscriptomicsRNA-seq on IGDQ-exposed MDA-MB-231 human breast cancer cell line
Breast cancer is the first type of cancer in term of incidence in the world with only 36% of survival at 5 years. This poor prognosis is mainly due to metastasis formation. Cell migration is a key process in nature and the understanding of its complex mechanisms has a crucial importance in biomateri...
ORGANISM(S): Homo sapiens 
2023-03-01 | E-MTAB-10477 | biostudies-arrayexpress
TranscriptomicsExpression data from MDA-MB-231 cells exposed to hypoxia and/or paclitaxel or epirubicin
Hypoxia protects cancer cells from chemotherapeutic drug-induced cell death. We used microarrays to detail the changes in gene expression underlying hypoxia-induced chemoresistance in cancer cells. MDA-MB-231 were exposed to paclitaxel or epirubicin under normoxia or hypoxia for 16hours, then RNA wa...
ORGANISM(S): Homo sapiens 
2012-07-02 | E-GEOD-39042 | biostudies-arrayexpress
Sort   by:  
 Page size