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Limited Evidence of Microexon Skipping in Parkinson’s Disease and Spinocerebellar Ataxia Type 3
Background: Microexons are short exonic sequences of 3–30 nucleotides that undergo alternative splicing and have been implicated in several neurodevelopmental disorders. However, their potential contribution to neurodegenerative diseases remains insufficiently characterized. Methods: We performed a ...
ORGANISM(S): Homo sapiens 
2026-09-22 | GSE329154 | GEO
Control of pancreatic islet function and glucose homeostasis by a novel microexon program misregulated in type 2 diabetes
Pancreatic islets control glucose homeostasis by the balanced secretion of insulin and other hormones, and its abnormal function causes diabetes or hypoglycemia. Here, we uncover a conserved program of alternative microexons included in mRNAs of islet cells, particularly in genes involved in vesicle...
ORGANISM(S): Homo sapiens Mus musculus Rattus norvegicus 
2022-12-14 | GSE198906 | GEO
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