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TranscriptomicsDifferences in gene expression patterns in mouse embryonic fibroblast Flp-In-3T3 cell lines stably expressing Pax6 or Pax6(5a).
Novel target genes for the two transcription factor isoforms Pax6 and Pax6(5a) were identified by generating mouse embryonic fibroblast cell lines stably expressing either Pax6 or Pax6(5a), and comparing their gene expression pattern with the original mouse embryonic fibroblast cell line. Flp-In-3T3...
ORGANISM(S): Mus musculus 
2012-03-22 | E-GEOD-31402 | biostudies-arrayexpress
TranscriptomicsKnockdown of the transcription factor PAX6 by short hairpin RNA in the adenocarcinoma cell line HPAFII reveal changes in gene expression of several cancer relevant genes
PAX6 is an evolutionary conserved transcription factor important for normal development of the CNS, eye and pancreas. Its role in cancer is however poorly understood as both tumor suppressive- and oncogenic properties have been reported. We generated a pancreatic adenocarcinoma cell line (HPAFII) we...
ORGANISM(S): Homo sapiens 
2020-07-01 | E-MTAB-5416 | biostudies-arrayexpress
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