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TranscriptomicsmicroRNA expression profiling of various C57Bl/6 myeloid cell populations
microRNAs are assumed to fine-tune cellular mRNA expression levels predisposing them for the control of cell development and cell fates. However, despite increasing appreciation of the role of miRNAs in controlling myeloid cell functions and some evidence for their contribution in in vitro monocyte ...
ORGANISM(S): Mus musculus 
2012-11-22 | E-GEOD-42434 | biostudies-arrayexpress
UnknownMyeloid transformation by MLL-ENL depends strictly on C/EBP.
Not available
S-EPMC7652399 | biostudies-literature
TranscriptomicsExpression data from in vitro derived dendritic cells generated in the presence of FLT3-L from wt and miR-142-/- BM cells
2 types of dendritic cells (DCs) can be generated in vitro in the presence of Flt3-L: CD4+ equivalent CD24- DCs and CD8+ equivalent CD24+ DCs. miR-142-/- mice show a severe defect in the generation of CD4+ equivalent CD24- DCs. To understand the underlying mechanism, RNA expression was analyzed by A...
ORGANISM(S): Mus musculus 
2012-11-16 | E-GEOD-42325 | biostudies-arrayexpress
TranscriptomicsmRNA expression of Qa2+ and Qa2- CD4+ thymocytes isolated from WT and miR-142-/- mice
Developing CD4+ T-cells in the thymus mature from CD69+Qa2- cells to CD69-Qa2+ T-cells. This maturation is accombanied by increased expression of CD62L and S1PR1 in Qa2+ cells, which allows mature T-cells to emigrate from the thymus to the periphery. However, miR-142-/- mice are characterized by an ...
ORGANISM(S): Mus musculus 
2013-06-14 | E-GEOD-47909 | biostudies-arrayexpress
TranscriptomicsThe lifespan and kinetics of human Dendritic Cell subsets and their precursors in health and inflammation
To probe the phenotype of the cDC compartment during pathology, we developed a simplified human experimental skin blister model to sample infiltrating cells in order to examine the function and kinetics of DC populations in response to a bacterial insult in healthy individuals. ASDC were recruited t...
ORGANISM(S): Homo sapiens 
2024-09-24 | E-MTAB-14451 | biostudies-arrayexpress
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