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ProteomicsInsights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis
Pulmonary alveolar microlithiasis is an autosomal recessive lung disease caused by a deficiency in the pulmonary epithelial Npt2b sodium-phosphate co-transporter that results in accumulation of phosphate and formation of hydroxyapatite microliths in the alveolar space. The single cell transcriptomic...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-02-16 | MSV000091302 | MassIVE
ProteomicsAn Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells - B2AR_DOR
SRM assays were generated for selected interactors of B2AR and DOR(MSV000084857), as well as for localization controls and ribosomal proteins (RPL18A, RPL28, RPL3, RPL35A, RPL6) as internal controls for normalization (Table S5 in publication). SRM assay generation was performed using Skyline. For al...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-02-17 | MSV000084966 | MassIVE
ProteomicsAn Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells - B2AR_localization
SRM assays were generated for selected interactors of B2AR and DOR (MSV000084857), as well as for localization controls and ribosomal proteins (RPL18A, RPL28, RPL3, RPL35A, RPL6) as internal controls for normalization (Table S5 in publication). We selected localization markers for different cellular...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-02-17 | MSV000084967 | MassIVE
ProteomicsA method for spatially and temporally resolved protein network interrogation in living cells
Cells operate through protein interaction networks organized in space and in time, but current methods to interrogate such biology typically resolve only one of these dimensions. Here, we describe a method to resolve both dimensions simultaneously using proximity labeling mediated by engineered asco...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-01-29 | MSV000084857 | MassIVE
UnknownThe African Critical Illness Outcomes Study (ACIOS): a point prevalence study of critical illness in 22 nations in Africa.
Not available
S-EPMC11872788 | biostudies-literature
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