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UnknownGPR40 partial agonist MK-2305 lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production.
Not available
S-EPMC5441580 | biostudies-literature
UnknownDiscovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor.
Not available
S-EPMC4716590 | biostudies-literature
UnknownDiscovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide Hydrolase.
Not available
S-EPMC4027136 | biostudies-literature
UnknownEscherichia coli K-12: a cooperatively developed annotation snapshot--2005.
Not available
S-EPMC1325200 | biostudies-literature
MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
TranscriptomicsPathways leading to phosphorylation of p450c17 and to the post-translational regulation of androgen biosynthesis
Cytochrome P450c17 (P450c17) is the single enzyme that catalyzes steroid 17alpha-hydroxylase and 17,20 lyase activities and hence is the crucial decision-making step that determines the class of steroid made in a steroidogenic cell. Although both activities are catalyzed on a single active site, the...
ORGANISM(S): Homo sapiens 
2013-02-15 | E-GEOD-44311 | biostudies-arrayexpress
UnknownTryptophan stabilizes His-heme loops in the denatured state only when it is near a loop end.
Not available
S-EPMC3341509 | biostudies-literature
UnknownRandomized trial of hypofractionated external-beam radiotherapy for prostate cancer.
Not available
S-EPMC3805927 | biostudies-literature
UnknownDiscovery of MK-7725, A Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity.
Not available
S-EPMC4025675 | biostudies-literature
UnknownClinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases.
Not available
S-EPMC4673667 | biostudies-literature
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