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TranscriptomicsA Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-derived Human Breast Cancer Xenografts
Translational breast cancer research is hampered by difficulties in obtaining and studying primary human breast tissue, and by the lack of in vivo preclinical models that reflect patient tumor biology accurately. In an effort to overcome these limitations, we propagated a cohort of human breast tumo...
ORGANISM(S): Homo sapiens 
2013-06-25 | E-GEOD-34412 | biostudies-arrayexpress
Unknown3, 4-Didehydroretinol kinetics differ during lactation in sows on a retinol depletion regimen and the serum:milk 3, 4-didehydroretinol:retinol ratios are correlated.
Not available
S-EPMC3056575 | biostudies-literature
MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with...

2022-02-10 | MTBLS718 | MetaboLights
UnknownCommon Coding Variants in <i>SCN10A</i> Are Associated With the Nav1.8 Late Current and Cardiac Conduction.
Not available
S-EPMC6377236 | biostudies-literature
UnknownLack of Virological Suppression Among Young HIV-Positive Adults in Botswana.
Not available
S-EPMC6069598 | biostudies-literature
UnknownDisability, psychological distress and quality of life in relation to cancer diagnosis and cancer type: population-based Australian study of 22,505 cancer survivors and 244,000 people without cancer.
Not available
S-EPMC7708114 | biostudies-literature
UnknownSurvival Outcomes by TP53 Mutation Status in Metastatic Breast Cancer.
Not available
S-EPMC6050977 | biostudies-literature
TranscriptomicsMicroarray Innovations in LEukemia (MILE) study: Stage 1 data
An International Multi-Center Study to Define the Clinical Utility of Microarray–Based Gene Expression Profiling in the Diagnosis and Sub-classification of Leukemia (MILE Study) Established in 2005, the MILE (Microarray Innovations in LEukemia) study research program included 11 participating cente...
ORGANISM(S): Homo sapiens 
2009-09-30 | E-GEOD-13159 | biostudies-arrayexpress
ProteomicsCharacterization of proteome changes after 48 hours of TR-57 (ClpP agonist) treatment
ONC201 is a first-in-class, FDA approved small molecule activator of the mitochondrial ATP-dependent caseinolytic peptidase P (ClpP). This and other related small molecules referred to as ClpP agonists, exert antiproliferative effects in several cancer cell types. We report that ONC201 and highly p...
ORGANISM(S): Homo sapiens (Human) 
2026-09-21 | PXD067842 | Pride
Cell cycle arrest Mitochondrial metabolism Regulation of cell death Clpp agonist Dna damage Triple-negative breast cancer Senescence 
UnknownA randomized controlled trial to investigate the use of acute coronary syndrome therapy in patients hospitalized with COVID-19: the COVID-19 Acute Coronary Syndrome trial.
Not available
S-EPMC10204350 | biostudies-literature
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