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TranscriptomicsTranscriptional analysis of quorum sensing null strain in Yersinia pestis CO92 at 30°C
Yersinia pestis is the etiology of plague that is able to sense cell density by quorum sensing. The function of quorum sensing in Y.pestis is not clear. Here, the process of quorum sensing was investigated by comparing transcript profiles when three quorum sensing synthase genes are knocked out. Two...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-20217 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of ypeIR mutation in Yersinia pestis at 37°C
The etiologic agent of bubonic plague, Yersinia pestis, senses cell density-dependent chemical signals to synchronize transcription between cells of the population in a process named quorum sensing. Though the closely related enteric pathogen Y. pseudotuberculosis uses quorum sensing system to regul...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30341 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of Yersinia pestis AHL quorum sensing at 37°C
Quorum sensing is a cell to cell communication process that involves chemical signaling. Yersinia pestis, the agent of plague, has two functional AHL quorum sensing systems Ysp and Ype. For several reasons, it was not clear what effect AHL pathways have on virulence gene expression and survival in t...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30331 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of Yersinia pestis Ype AHL quorum sensing at 30°C
Quorum sensing is a cell to cell communication process that involves chemical signaling. Yersinia pestis, the agent of plague, has two functional AHL quorum sensing systems Ysp and Ype. For several reasons, it was not clear what effect AHL pathways have on virulence gene expression and survival in t...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30332 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of Yersinia pestis Ysp AHL quorum sensing at 37°C
Quorum sensing is a cell to cell communication process that involves chemical signaling. Yersinia pestis, the agent of plague, has two functional AHL quorum sensing systems Ysp and Ype. For several reasons, it was not clear what effect AHL pathways have on virulence gene expression and survival in t...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30328 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of Yersinia pestis Ysp AHL quorum sensing at 30°C
Quorum sensing is a cell to cell communication process that involves chemical signaling. Yersinia pestis, the agent of plague, has two functional AHL quorum sensing systems Ysp and Ype. For several reasons, it was not clear what effect AHL pathways have on virulence gene expression and survival in t...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30329 | biostudies-arrayexpress
TranscriptomicsLuxS/AI-2 quorum sensing microarray comparison in Yersinia pestis at 30°C
The AI-2 quorum-sensing system has been linked to diverse phenotypes and regulatory changes in pathogenic bacteria. In strain CO92, the AI-2 signal is produced in a luxS-dependent manner, reaching maximal levels of 2.5 μM in late logarithmic growth, and both wild type and pigmentation mutant strain...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30108 | biostudies-arrayexpress
Transcriptomics3 quorum sensing signals add in microarray comparison in Yersinia pestis at 30°C
The quorum-sensing system has been linked to diverse phenotypes and regulatory changes in pathogenic bacteria. In strain CO92, the AI-2 signal is produced in a luxS-dependent manner, reaching maximal levels of 2.5 μM in late logarithmic growth, and both wild type and pigmentation mutant strains mad...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30109 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of temperature regulation in Yersinia pestis
Temperature is a key environmental factor for facultative pathogens during the host adaptation response. To assess the functional role of temperature in Yersinia pestis, a microarray study was conducted comparing the Δpgm (pigmentation-negative) R88 strain grown at 37°C or 30°C. Six independent R...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30333 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of AHLs signal treatment at 30°C
Yersinia pestis, the etiological agent of plague, is able to sense cell density by quorum sensing. The function of quorum sensing in Y. pestis is not clear. Here, the process of AHL quorum sensing was investigated by comparing transcript profiles when two AHL quorum-sensing signals are added in. The...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30238 | biostudies-arrayexpress
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