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TranscriptomicsIdentification of genes differentially expressed in lung cancer cells after the transfection of miR-221 or miR-222.
To evaluate involvement of miR-221 and miR-222 in lung cancer, we investigated the effects of miR-221 and miR-222 overexpression on six lung cancer cell lines as well as one immortalized normal human bronchial epithelial cell line. Two cell lines, H3255 and H1299 with no replicates were studied. Ce...
ORGANISM(S): Homo sapiens 
2015-05-22 | E-GEOD-57676 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of MCF10A (miR-221/222 vs control)
Analysis of gene expression of MCF10A to identify the targets of miR-221 and miR-222 Keywords: MCF10, miR-221, miR-222 RNA profiles of human MCF10A cell line
ORGANISM(S): Homo sapiens 
2011-06-14 | E-GEOD-29327 | biostudies-arrayexpress
TranscriptomicsmiR-222 is necessary for exercise-induced cardiac growth and protects against pathological cardiac remodeling.
miR-222 overexpression leads to promotion of proliferation and hypertrophy and inhibition of apoptosis in in primary neonatal rat ventricular cardiomyocytes (NRVMs). Isolated primary neonatal rat ventricular cardiomyocytes were plated in 6 cm BD Primaria tissue culture dishes. Transfection of microR...
ORGANISM(S): Rattus norvegicus 
2016-03-03 | E-GEOD-59641 | biostudies-arrayexpress
TranscriptomicsGenome-wide miRNA profile of MCF7 cells overexpressing wild-type and mutant miR-222
MCF7 cells were infected with retrovirus to overexpress wild-type and mutant miR-222 Measure miRNA expression level in MCF7 cells after overexpressing wild-type and mutant miR-222
ORGANISM(S): Homo sapiens 
2015-02-05 | E-GEOD-64363 | biostudies-arrayexpress
GenomicsThe oncogenic microRNA miR-222 promotes human LINE-1 retrotransposition
The oncogenic microRNA miR-222 promotes human LINE-1 retrotransposition
PRJNA1141495 | ENA
ProteomicsmicroRNA-222 Attenuates Mitochondrial Dysfunction Induced by Transmissible Gastroenteritis Virus via Targeting Thrombospondin-1 and Inhibiting Cluster of Differentiation 47
Transmissible gastroenteritis virus (TGEV) is a member of Coronaviridae family. Our previous research showed that TGEV infection could induce mitochondrial dysfunction and up-regulat miR-222 level. Therefore, we presumed that miR-222 might be implicated in regulating mitochondrial dysfunction induce...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2018-12-19 | PXD010927 | Pride
Proteomics Microrna-222 Mitochondrial dysfunction Transmissible gastroenteritis virus Thrombospondin-1 (thbs1) Cluster of differentiation 47 (cd47) 
GenomicsmiR-221/222 drive synovial fibroblast expansion and pathogenesis of TNF-mediated arthritis
miR-221/222 drive synovial fibroblast expansion and pathogenesis of TNF-mediated arthritis
PRJNA868177 | ENA
GenomicsmiR-222 isoforms are differentially regulated by type-I interferon
miR-222 isoforms are differentially regulated by type-I interferon
PRJEB22632 | ENA
TranscriptomicsGene expression profiling of MCF10A (miR-221/222 vs control)
Analysis of gene expression of MCF10A to identify the targets of miR-221 and miR-222 Keywords: MCF10, miR-221, miR-222
ORGANISM(S): Homo sapiens 
2011-06-14 | GSE29327 | GEO
TranscriptomicsThe oncogenic microRNA miR-222 promotes human LINE-1 retrotransposition
The Long Interspersed Element-1 (LINE-1) contributes significantly to carcinogenesis and to tumor heterogeneity in many cancer types, including hepatocellular carcinoma (HCC), by its autonomous retrotransposition (RTP) and by its ability to retrotranspose some non-autonomous transposable elements. P...
ORGANISM(S): Homo sapiens 
2025-06-16 | GSE273369 | GEO
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