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TranscriptomicsIdentification and characterization of novel and conserved microRNAs in self-grafted and grafted watermelon by high-throughput sequencing
In this study, Solexa sequencing technology has been used to discover small RNA populations of self-grafted watermelon and grafted watermelon (bottle gourd and squash were used as rootstocks). A total of 11,458,476, 11,614,094 and 9,339,089 raw reads representing 2,957,751, 2,880,328 and 2,964,990 u...
ORGANISM(S): Citrullus lanatus 
2011-10-26 | E-GEOD-33209 | biostudies-arrayexpress
TranscriptomicsAge- and Obesity Induced Decline of Brown Fat Function as Consequence of Impaired miR-328 Dependent Silencing of Bace1
Activated brown adipose tissue contributes to control of energy and glucose homeostasis in rodents and humans. Defining cell-autonomous processes underlying BAT differentiation and activation may thus reveal novel therapeutic targets for obesity and type 2 diabetes mellitus intervention. Here we sho...
ORGANISM(S): Mus musculus 
2015-06-17 | E-GEOD-69913 | biostudies-arrayexpress
UnknownCOVID-19 in children with neuromuscular disorders.
Not available
S-EPMC7775833 | biostudies-literature
TranscriptomicsIdentification of differentially expressed miRNAs in BM+ vs. BM- lung cancer samples
Brain metastasis (BM) can affect up to 25% of non-small cell lung cancer (NSCLC) patients during their lifetime. Efforts to characterize patients that will develop BM have been fairly disappointing. Small non-coding microRNAs (miRNAs) regulate the expression of target mRNAs by repressing their trans...
ORGANISM(S): Homo sapiens 
2011-02-16 | E-GEOD-23019 | biostudies-arrayexpress
TranscriptomicsGene profiling of mouse brain infected with scrapie strain 22A_End-point analysis
This SuperSeries is composed of the following subset Series: GSE12321: Brain_22A-Scrapie_End-point_PR04-39-to-46_using_GPL7118 GSE12322: Brain_22A-Scrapie_End-point_PR06-11-to-14_using_GPL7121 Refer to individual Series
ORGANISM(S): Mus musculus 
2010-05-19 | E-GEOD-12354 | biostudies-arrayexpress
TranscriptomicsBrain_22A-Scrapie_End-point_PR06-11-to-14_using_GPL7121
Examining the transcriptional change in whole mouse (VM) brain miRNA expression during prion (22A) induced neurodegeneration in order to identify miRNAs that are differentially expressed. MicroRNAs (miRNAs) are small, non-coding RNA molecules which are emerging as key regulators of numerous cellular...
ORGANISM(S): Mus musculus 
2010-05-19 | E-GEOD-12322 | biostudies-arrayexpress
TranscriptomicsIdentification of the receptor tyrosine kinase AXL in triple negative breast cancer as a novel target for the human miR-34a microRNA (miRNA study)
Triple negative breast cancer (TNBC) is histologically characterized by the absence of the hormone receptors estrogen and progesterone, in addition to having a negative immunostain for HER-2. The aggressiveness of this disease and lack of targeted therapeutic options for treatment is of high clinic...
ORGANISM(S): Homo sapiens 
2010-12-31 | E-GEOD-21719 | biostudies-arrayexpress
UnknownDurvalumab Plus Carboplatin/Paclitaxel Followed by Maintenance Durvalumab With or Without Olaparib as First-Line Treatment for Advanced Endometrial Cancer: The Phase III DUO-E Trial.
Not available
S-EPMC10824389 | biostudies-literature
UnknownValidation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery.
Not available
S-EPMC8855527 | biostudies-literature
UnknownEffects of icosapent ethyl according to baseline residual risk in patients with atherosclerotic cardiovascular disease: results from REDUCE-IT.
Not available
S-EPMC11873788 | biostudies-literature
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