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GenomicsGenome-wide binding of STAT3 in peritoneal macrophages
To try to identify the mechanism of STAT3’s indirect action we have used a genomic approach to map the binding sites of STAT3 within the genome and also used RNA-seq technology to map the changes in RNA expression and transcript isoforms in response to IL-10. Examination of STAT3 binding by ChIP-s...
ORGANISM(S): Mus musculus 
2012-02-13 | E-GEOD-31529 | biostudies-arrayexpress
TranscriptomicsTranscriptome changes in IL-10 treated peritoneal macrophages
To try to identify the mechanism of STAT3s indirect action we have used a genomic approach to map the binding sites of STAT3 within the genome and also used RNA-seq technology to map the changes in RNA expression and transcript isoform abundance in response to IL-10. Examination of transcriptome cha...
ORGANISM(S): Mus musculus 
2012-02-13 | E-GEOD-31530 | biostudies-arrayexpress
GenomicsGenome-wide analysis of STAT3-binding and gene expression changes in peritoneal macrophages upon interleukin-10 stimulation
This SuperSeries is composed of the following subset Series: GSE31529: Genome-wide binding of STAT3 in peritoneal macrophages GSE31530: Transcriptome changes in IL-10 treated peritoneal macrophages Refer to individual Series
ORGANISM(S): Mus musculus 
2012-02-13 | E-GEOD-31531 | biostudies-arrayexpress
TranscriptomicsSystematic RNA-seq analysis of the early events of CD4+ T cell activation
RNA-seq was used to look at the transcriptome changes and the early events of T cell receptor stimulation in CD4+ T cells CD4+ T cells were stimulated with immobilised anti-CD3/CD28 antibodies for 4 hours and RNA was extracted and subjected to RNA-seq analysis.
ORGANISM(S): Mus musculus 
2012-08-08 | E-GEOD-34550 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of IL-10 treatment of wildtype and Ptpn1-/- knockout peritoneal macrophages
We report here the deep sequencing of the mRNA from peritoneal exudate cells (macrophages) purified from wildtype or Ptpn1 (PTP1B) knockout mice, either treated or untreated with IL-10. In periotenal macrophages IL-10 activates the transcription factor STAT3 to execute and anti-inflammatory gene exp...
ORGANISM(S): Mus musculus 
2014-05-12 | E-GEOD-49449 | biostudies-arrayexpress
GenomicsThe Transcriptional Programme Controlled by Scl/Tal1 Gene during Early Embryonic Haematopoietic Development
The basic-helix-loop-helix transcription factor Scl/Tal1 controls the development and subsequent differentiation of haematopoietic stem cells (HSCs). However, since few Scl target genes have been validated to date, the underlying mechanisms have remained largely unknown. Here we have employed ChIP...
ORGANISM(S): Mus musculus 
2009-06-19 | E-GEOD-15806 | biostudies-arrayexpress
UnknownThe complement of protein kinases of the microsporidium Encephalitozoon cuniculi in relation to those of Saccharomyces cerevisiae and Schizosaccharomyces pombe.
Not available
S-EPMC2078597 | biostudies-literature
TranscriptomicsTranscription profiling of differentiated human blood cells: The HaemAtlas
Transcription profiling of highly purified blood cells from normal individuals
ORGANISM(S): Homo sapiens 
2009-02-06 | E-TABM-633 | biostudies-arrayexpress
UnknownOutcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic.
Not available
S-EPMC7753519 | biostudies-literature
UnknownDelaying surgery for patients with a previous SARS-CoV-2 infection.
Not available
S-EPMC7537063 | biostudies-literature
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