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TranscriptomicsNovel age related alterations revealed by a comparative kinetic transcriptome analysis of naïve CD4+ and CD8+ T cells from young and old animals.
Define,(a) intrinsic differences and (b) changes occuring upon TCR activation in genetic profiles of naive CD4+ and CD8+ T cells from young and old animals, to identify candidate genes altered in old T cells involved in impairement of immune response in order to restore immune function in the old. A...
ORGANISM(S): Mus musculus 
2011-03-24 | E-GEOD-28165 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of interferon-stimulated genes in primary cells and immortalized cell lines
Analysis of interferon-stimulated genes (ISGs) in various primary cells and immortalized cell lines, following type 1 interferon (IFN) treatment. Some cell types become resistant to HIV-1 infection following type 1 interferon treatment (such as macrophages, THP-1, PMA-THP-1, U87-MG cells and to a le...
ORGANISM(S): Homo sapiens 
2013-09-13 | E-GEOD-46599 | biostudies-arrayexpress
UnknownAdoptive T-cell therapy for Leukemia.
Not available
S-EPMC4452065 | biostudies-literature
UnknownB7-H1 expression on old CD8+ T cells negatively regulates the activation of immune responses in aged animals.
Not available
S-EPMC3919800 | biostudies-literature
UnknownCD8+ T Lymphocyte Epitopes From The Herpes Simplex Virus Type 2 ICP27, VP22 and VP13/14 Proteins To Facilitate Vaccine Design And Characterization.
Not available
S-EPMC3972665 | biostudies-literature
UnknownCancer Cell Small Molecule Secretome Induces the Immune Checkpoint NKG2A and Dysfunction of Human CD8+ T Cells.
Not available
S-EPMC11220743 | biostudies-literature
UnknownHarnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments.
Not available
S-EPMC10327392 | biostudies-literature
UnknownComparative kinetic analyses of gene profiles of naive CD4+ and CD8+ T cells from young and old animals reveal novel age-related alterations.
Not available
S-EPMC3919687 | biostudies-literature
UnknownGraft versus self (GvS) against T-cell autoantigens is a mechanism of graft-host interaction.
Not available
S-EPMC5137740 | biostudies-literature
UnknownCytokine Release Syndrome and Neurotoxicity Following CD19 CAR-T in B-Cell Lymphoma.
Not available
S-EPMC12622908 | biostudies-literature
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