Sort   by:  
 Page size 
TranscriptomicsGene Expression analysis comparison between control and CC214-2 resistant GBM39 xenografts
Here we present gene expression analysis data on two vehicle treated and two CC214-2 (an mTOR kinase inhibitor) resistant GlioBlastoma Multiforme 39 (GBM39) xenografts, showing that the expressioin profiles of 88 genes are significantly different between the two groups. GBM39 primary neurospheres we...
ORGANISM(S): Homo sapiens 
2014-11-19 | E-GEOD-63387 | biostudies-arrayexpress
TranscriptomicsCopy number variation comparison between control and CC214-2 resistant GBM39 xenografts
Here we present genome-wide copy number variation data on two vehicle treated and two CC214-2 (an mTOR kinase inhibitor) resistant GlioBlastoma Multiforme 39 (GBM39) xenografts, showing the absence of significant differences between the two groups, demonstrating that resistance to CC214-2 is due to ...
ORGANISM(S): Homo sapiens 
2013-12-06 | E-GEOD-53042 | biostudies-arrayexpress
GenomicsMus musculus
Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression
PRJNA276065 | ENA
UnknownRTOG 0211: a phase 1/2 study of radiation therapy with concurrent gefitinib for newly diagnosed glioblastoma patients.
Not available
S-EPMC4199329 | biostudies-literature
TranscriptomicsEGFRvIII vs. Control - xenograft glioblastomas
Glioblastoma cell lines were xenografted onto mice and resulting tumors were profiled by microarray. Xenograft recipient mice were NOD/SCID/gamma (NSG) male mice 3 months old. In this set, 6 total samples were analyzed. There were three biological replicates for each of two conditions: EGFRvIII co...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-46028 | biostudies-arrayexpress
TranscriptomicsmTOR inhibitors synergistically induce regression, reversal of gene expression and autophagy in hepatocellular carcinoma
The mTOR-allosteric inhibitor, RAD001, in combination with a PI3K/mTOR ATP-site competitive inhibitor, BEZ235, causes gene reprogramming, autophagy and tumor regression, in a mouse model approximating human HCC with poor prognosis, leading to an investigator Phase 1B-2 clinical trial. Comparative st...
ORGANISM(S): Mus musculus 
2012-07-11 | E-GEOD-37129 | biostudies-arrayexpress
TranscriptomicsEGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling
Epidermal Growth Factor Receptor (EGFR) gene amplification and mutations are the most common oncogenic events in Glioblastoma (GBM), but the mechanisms by which they promote aggressive tumor growth are not well understood. Here, through integrated epigenome and transcriptome analyses of cell lines, ...
ORGANISM(S): Homo sapiens 
2015-09-14 | E-GEOD-72468 | biostudies-arrayexpress
Sort   by:  
 Page size