Mitochondrial electron transport

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Unknown (2238)
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Caenorhabditis elegans (20)
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Corynebacterium glutamicum ATCC 13032 (2)
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Pseudoalteromonas sp. A2 (1)
Methyloversatilis universalis FAM5 (1)
Phlebiopsis gigantea (1)
Brucella suis 1330 (1)

Organisms

Mus musculus (132)
Homo sapiens (83)
Caenorhabditis elegans (10)
Rattus norvegicus (9)
Drosophila melanogaster (7)
Arabidopsis thaliana (6)
Plasmodium falciparum (3)
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Oncorhynchus mykiss (1)
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Gallus gallus (1)
mouse gut metagenome (1)
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Repository

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geo (275)
pride (124)
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Tissue

Cell culture (20)
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Liver (3)
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Cardiovascular system disease (1)
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Technology Type

Mass Spectrometry (127)
Shotgun proteomics (59)
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Bottom-up proteomics (36)
Mass spectrometry assay (17)
Data-dependent acquisition (16)
Affinity purification coupled with mass spectrometry proteomics (11)
Gel-based experiment (11)
Data-independent acquisition (9)
Top-down proteomics (8)
NMR spectroscopy (5)
SWATH MS (4)
DiaPASEF (3)
EI (2)
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Chemical cross-linking coupled with mass spectrometry proteomics (2)
Illumina HiSeq 2500, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500 (1)
ILLUMINA, Illumina HiSeq 2000 (1)
ESI (1)
SRM/MRM (1)

Instrument Platform

Illumina NovaSeq 6000 (14)
Q Exactive (10)
Orbitrap Fusion Lumos (7)
Illumina HiSeq 2500 (5)
Orbitrap Eclipse (5)
Orbitrap Fusion (5)
Illumina HiSeq 2000 (4)
NextSeq 500 (4)
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Q Exactive Plus (4)
Illumina HiSeq 4000 (3)
GenePix 4000A [Axon Instruments] (2)
NextSeq 2000 (2)
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Qiagen RNAeasy, Bioanalyzer QubitFluorometer, Agilent 2100, RNA Pico 6000 chip (1)
Illumina TruSeq (1)
Infors-HT Labfors chemostat (1)
Ilumina HiScan H166 (1)
Not applicable (1)
Illumina iScan (1)
Dell PowerEdge R820 (1)
ScanArray Lite [PerkinElmer] (1)
GenePix 4000B [Axon Instruments] (1)
Affymetrix Fluidics Station 400 (1)
Axon GenePix 4000B scanning hardware (1)
DNBSEQ-G400 (1)
Illumina HiSeq 1500 (1)

Publication Date

2025 (90)
2024 (86)
2026 (82)
2013 (62)
2022 (61)
2010 (58)
2021 (56)
2023 (49)
2020 (43)
2014 (42)
2012 (41)
2008 (41)
2016 (40)
2015 (37)
2011 (37)
2019 (31)
2009 (31)
2018 (24)
2007 (21)
2017 (17)
2006 (12)
2004 (5)
2005 (3)

UNIPROT ID/AC

1433E_HUMAN (2)
1433F_HUMAN (2)
1433G_HUMAN (2)
1433S_HUMAN (2)
1433T_HUMAN (2)
1433Z_HUMAN (2)
2A5A_HUMAN (2)
2A5D_HUMAN (2)
2A5E_HUMAN (2)
2A5G_HUMAN (2)
2AAA_HUMAN (2)
2AAB_HUMAN (2)
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2ABD_HUMAN (2)
3HAO_HUMAN (2)
3HIDH_HUMAN (2)
41_HUMAN (2)
4EBP1_HUMAN (2)
4EBP2_HUMAN (2)
4F2_HUMAN (2)
5NT1A_HUMAN (2)
5NT3A_HUMAN (2)
5NTC_HUMAN (2)
5NTD_HUMAN (2)
6PGD_HUMAN (2)
6PGL_HUMAN (2)
8ODP_HUMAN (2)
9606.ENSP00000228938 (2)
9606.ENSP00000233596 (2)
9606.ENSP00000291295 (2)

CHEBI ID

CHEBI:18012 (14)
CHEBI:6650 (13)
CHEBI:16027 (13)
CHEBI:17568 (13)
CHEBI:16704 (13)
CHEBI:17596 (13)
CHEBI:30769 (13)
CHEBI:16856 (12)
CHEBI:17562 (12)
CHEBI:32816 (12)
CHEBI:15422 (11)
CHEBI:16761 (9)
CHEBI:17234 (8)
CHEBI:16908 (7)
CHEBI:15846 (7)
CHEBI:17138 (6)
CHEBI:15351 (6)
CHEBI:15361 (2)
CHEBI:29108 (2)
CHEBI:17980 (1)
CHEBI:16136 (1)
CHEBI:16189 (1)
CHEBI:17709 (1)
CHEBI:17561 (1)
CHEBI:15377 (1)
CHEBI:24636 (1)
CHEBI:16236 (1)
CHEBI:15379 (1)
CHEBI:16288 (1)
CHEBI:18361 (1)

Metabolite Name

Inosine (16)
Hypoxanthine (15)
Creatine (14)
Betaine (13)
Taurine (13)
Uracil (13)
Guanosine (13)
Creatinine (13)
Adenine (12)
Cytidine (12)
Glycine (11)
Adenosine (11)
Guanine (11)
Xanthine (11)
Uridine (11)
L-Tyrosine (11)
Glucose (10)
AMP (9)
Citrulline (9)
Choline (9)
L-Tryptophan (9)
L-Phenylalanine (9)
Dimethylglycine (8)
L-Alanine (8)
ADP (8)
Glutathione (8)
Ornithine (8)
Succinic acid (8)
Pantothenic acid (8)
Cholic acid (8)

First Public Date

2024 (50)
2026 (49)
2025 (41)
2022 (28)
2020 (26)
2023 (24)
2021 (24)
2014 (23)
2019 (17)
2018 (16)
2017 (10)
2015 (6)
2013 (4)
2016 (2)

Modelling Approach

Ordinary differential equation model (4)

Lab affiliation

Department of Inflammation and Immunity, Gastroenterology and Hepatology. Cleveland Clinic, Cleveland Ohio, USA (8)
Department of Inflammation and Immunity, Gastroenterology and Hepatology. Cleveland Clinic, Cleveland Ohio (3)
First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China (3)
Center for Molecular Biology of Heidelberg University (ZMBH), 69120 Heidelberg, Germany (2)
Head of Proteomics (2)
Institute for Clinical Biochemistry and Pathobiochemistry German Diabetes Center (DDZ) Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf Auf´m Hennekamp 65 40225 Düsseldorf, Germany (2)
Max-Planck-Institute for Biology of Ageing Department of Mitochondrial Proteostasis Joseph-Stelzmann-Str. 9b 50931 Cologne (2)
1 Departamento de Biología Molecular, Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM);2 Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), ISCIII; 3 Instituto de Investigación Hospital 12 de Octubre; 4 Instituto Madrileño de Estudios Avanzados (IMDEA) Food Institute, Universidad Autónoma de Madrid, 28049, Madrid, Spain. (1)
1. Cancer Signalling Research Group, School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, NSW, AUSTRALIA 2. Precision Medicine Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, AUSTRALIA 3. Paediatric Program, Mark Hughes Foundation Centre for Brain Cancer Research, College of Health, Medicine, and Wellbeing, Callaghan, NSW, AUSTRALIA (1)
Aarhus University, Denmark (1)
BioMediTech & Tampere University Hospital, Faculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34 (ARVO), FI-33520 Tampere, Finland (1)
Biological Chemistry and Drug Discovery, Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee (1)
Biomolecular Mass Spectrometry & Proteomics, Bijvoet Centre for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CH Utrecht, The Netherlands (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands (1)
CNIC (1)
Cardiovascular and Metabolic Diseases, Duke-NUS Medical School, Singapore (1)
Cell Biology, Harvard Medical School (1)
Cellular and Molecular Pharmacology, UCSF (1)
Center for Functional Protein Assemblies, Department of Bioscience, TUM School of Natural Sciences, Technical University of Munich, Ernst-Otto-Fischer-Straße 8, 85748 Garching, Germany. (1)
Center for Functional Protein Assemblies, TUM School of Natural Sciences, Technical University of Munich, Ernst-Otto-Fischer-Straße 8, 85748 Garching, Germany. (1)
Children's Research Institute University of Texas Southwestern Medical Center (1)
College of Biomedical Engineering & Instrument Science, Zhejiang University (1)
DZNE Munich Neuroproteomics Feodor-Lynen Str. 17 81377 Munich Germany (1)
Dana Farber Cancer Institute: Dept. of Cancer Biology Harvard Medical School: Department of Cell Biology (1)
Dana-Farber Cancer Institute, Department of Cancer Biology. Harvard Medical School, Department of Cell Biology. (1)
Department of Biochemistry & Pharmacology, Bio21 Institute, University of Melbourne (1)
Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA (1)
Department of Biochemistry and Molecular Biology, The Bio21 Molecular Science & Biotechnology Institute, University of Melbourne, Melbourne, Australia (1)
Department of Biochemistry and Molecular Biology, University of Calgary, Alberta, Canada; Department of Physiology and Pharmacology, University of Calgary, Alberta, Canada; The Hotchkiss Brain Institute, University of Calgary, Alberta, Canada; McCaig Institute for Bone and Joint Health, University of Calgary, Alberta, Canada. (1)
Department of Biochemistry and Pharmacology, The Bio21 Molecular Science & Biotechnology Institute, University of Melbourne, 30 Flemington Rd, Parkville Victoria 3052, Australia (1)

IsPrivate

False (5)

Model Flag

Non Kinetic (1)

Classification

protozoa (3)
fungi (1)

Study type

Transcription profiling by array (315)
RNA-seq of coding RNA (48)
Methylation profiling by array (11)
Unknown experiment type (8)
ChIP-seq (7)
Other (5)
RNA-seq of coding RNA from single cells (5)
RNA-seq of total RNA (4)
Transcription profiling by SAGE (3)
Comparative genomic hybridization by array (3)
Cell line - High-throughput sequencing (2)
Transcription profiling by tiling array (2)
ChIP-chip by array (2)
Methylation profiling by high throughput sequencing (2)
ChIP-chip by tiling array (1)
RNAi profiling by array (1)
CLIP-seq (1)
ScATAC-seq (1)
MicroRNA profiling by array (1)
RNA-seq of non coding RNA (1)

Release Date

2022 (252)
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2021 (215)
2024 (202)
2023 (197)
2020 (195)
2019 (153)
2016 (131)
2015 (128)
2018 (125)
2017 (116)
2014 (113)
2013 (103)
2010 (96)
2011 (83)
2012 (80)
2008 (68)
2009 (52)
2026 (44)
2007 (29)
2006 (22)
2004 (8)
2005 (5)
2003 (4)
2002 (2)
2001 (2)
2000 (2)

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Differential requirements for mitochondrial electron transport chain components in the adult murine liver - Lactate/Pyruvate Tolerance Test

Not available

ORGANISM(S): Mus musculus

ST002314 | MetabolomicsWorkbench

Differential requirements for mitochondrial electron transport chain components in the adult murine liver - Untargeted Metabolomics (qTOF)

Not available

ORGANISM(S): Mus musculus

ST002316 | MetabolomicsWorkbench

Differential requirements for mitochondrial electron transport chain components in the adult murine liver - in vivo glucose tracing

Not available

ORGANISM(S): Mus musculus

ST002315 | MetabolomicsWorkbench

Mitochondrial glutamine import sustains mitochondrial translation independent of glutaminolysis in cancer_GlnFlux_untargeted metabolites

Oxidative phosphorylation (OXPHOS) fulfills energy metabolism and biosynthesis through tricarboxylic acid (TCA) cycle and an intact electron transport chain (ETC). Mitochondrial glutamine import (MGI) replenishes TCA cycle through glutaminolysis, but its broader roles in cancer remains unclear. H...

2025-09-29 | MTBLS13074 | MetaboLights

Mitochondrial glutamine import sustains mitochondrial translation independent of glutaminolysis in cancer_targeted metabolites

2025-09-29 | MTBLS13076 | MetaboLights

Mitochondrial glutamine import sustains mitochondrial translation independent of glutaminolysis in cancer_A549 cell culture_untargeted metabolites_U_13gln/glc

2025-09-29 | MTBLS13075 | MetaboLights

Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics

Mitochondrial electron transport flavoprotein (ETF) insufficiency causes metabolic diseases known as a multiple acyl-CoA dehydrogenase deficiency (MADD). Although essential in muscle, we identified ETF dehydrogenase (ETFDH) as one of the most dispensable metabolic genes in neoplasia, and its expr...

2026-05-02 | MTBLS11048 | MetaboLights

Multi‐omics identify xanthine as a pro‐survival metabolite for nematodes with mitochondrial dysfunction

Aberrant mitochondrial function contributes to the pathogenesis of various metabolic and chronic disorders. Inhibition of insulin/IGF-1 signaling (IIS) represents a promising avenue for the treatment of mitochondrial diseases, although many of the molecular mechanisms underlying this beneficial effe...

2019-02-28 | MTBLS794 | MetaboLights

Genes expressed in age-induced mitochondrial DNA deletion mutation containing / Electron Transport abnormal cells

Muscle tissue was longitudinally characterized histologically for electron transport function by staining 1mm of quadriceps muscle at 70 micron intervals for the activities of two complexes in the mitochondrial electron transport chain, Cytochrome C Oxidase and Succinate Dehydrogenase. Unstained ser...

ORGANISM(S): Rattus norvegicus

2013-03-01 | E-GEOD-35607 | biostudies-arrayexpress

PRODH regultes naive pluripotency by influencing mitochondrial oxidative phosphorylation (Untargeted metabolomics)

Naïve human embryonic stem cells (hESCs) that resemble the pre-implantation epiblasts are fueled by a combination of aerobic glycolysis and oxidative phosphorylation, but their mitochondrial regulators are poorly understood. Here we report that, proline dehydrogenase (PRODH), a mitochondria-local...

2024-02-12 | MTBLS7840 | MetaboLights

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