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GenomicsHistone modifications induced by MDV infection at early cytolytic and latency phases
Background: Marek’s disease (MD) is a highly contagious, lymphomatous disease of chickens induced by a herpesvirus, Marek’s disease virus (MDV) that is the cause of major annual losses to the poultry industry. MD pathogenesis involves multiple stages including an early cytolytic phase and latency, a...
ORGANISM(S): Gallus gallus 
2015-04-17 | E-GEOD-65961 | biostudies-arrayexpress
GenomicsMarek's Disease Virus Infection Induces Differential Chromatin Marks and Tissue-specific effects in inbred chicken lines
Marek’s disease (MD) is a viral neoplastic disease in chickens caused by the MD virus (MDV). Successful vaccination strategies against MD have resulted in a progressive increase in the virulence of MDV and therefore, the understanding of genetic resistance to MD is considered crucial to the long-ter...
ORGANISM(S): Gallus gallus 
2013-01-01 | E-GEOD-33541 | biostudies-arrayexpress
TranscriptomicsChicken Spleen Tissues: MDV-infected vs non-infected in inbred lines 63, 72 & RCSM
Transcriptional profiling of chicken spleen tissues from Marek's disease virus (MDV) infected and non-infected control individuals from three inbred chicken lines 63, 72, RCSM with varying disease resistance characteristics. Line 63 is highly resistant; line 72 is highly susceptible; and line RCSM h...
ORGANISM(S): Gallus gallus 
2010-09-08 | E-GEOD-24017 | biostudies-arrayexpress
TranscriptomicsAnalysis of copy number variations among diverse cattle breeds
Genomic structural variation is an important and abundant source of genetic and phenotypic variation. Here we describe the first systematic and genome-wide analysis of copy number variations (CNVs) in modern domesticated cattle using array comparative genomic hybridization (array CGH), quantitative ...
ORGANISM(S): Bos taurus 
2010-03-02 | E-GEOD-19866 | biostudies-arrayexpress
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