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TranscriptomicsCombined Use of Laser Capture Microdissection and Microarray Analysis Identifies Locally Expressed Disease-Related Genes in Focal Regions of Psoriasis Vulgaris Skin Lesions
In this study, we sought to establish the usefulness of LCM on cDNA microarray analysis. We reported that LCM samples improved the sensitivity of detection of differentially expressed genes over conventional bulk tissue analysis. We also provided the new information of chemokine and its receptor int...
ORGANISM(S): Homo sapiens 
2012-01-30 | E-GEOD-26866 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of acute and chronic atopic dermatitis compared to normal skin
Atopic dermatitis (AD) is a common disease, with an increasing prevalence. The primary pathogenesis of the disease is still elusive, resulting in lack of specific treatments. The prevailing view is that AD is a biphasic, T-cell polarized disease, with Th2 predominating acute AD, and a switch to Th1 ...
ORGANISM(S): Homo sapiens 
2012-09-21 | E-GEOD-36842 | biostudies-arrayexpress
ProteomicsDemonstration of a complementary approach for genetic diagnosis of inborn errors of immunity using proteogenomic analysis
Genetic diagnosis plays a central role in the clinical management of patients with inborn errors of immunity (IEI). We proposed a novel method for diagnosing IEI using PBMC proteomics integrated with targeted RNA sequencing, providing notable insights into the pathogenesis of IEI. Data-independent a...
ORGANISM(S): Homo Sapiens (human) 
2023-11-25 | PXD038352 | JPOST Repository
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