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ProteomicsProteomic investigation of a mixed microbial culture synthesizing polyhydroxyalkanoates from fermented dairy manure under aerobic feast-famine conditions
Polyhydroxyalkanoates (PHAs) are bio-based, biodegradable polyesters that can be produced from organic-rich waste streams using mixed microbial cultures. To maximize PHA production, mixed microbial cultures may be enriched for PHA-producing bacteria with a high storage capacity through the impositi...
ORGANISM(S): environmental samples 
2017-01-31 | PXD003126 | Pride
Polyhydroxyalkanoates Two-dimensional electrophoresis Mixed microbial culture 
MetabolomicsIntegration of time-series meta-omics data reveals how microbial ecosystems respond to disturbance
The development of reliable, mixed-culture biotechnological processes hinges on understanding how microbial ecosystems respond to disturbances. Here we reveal extensive phenotypic plasticity and niche complementarity in oleaginous microbial populations from a biological wastewater treatment plant. W...
2021-04-06 | MTBLS2021 | MetaboLights
MetabolomicsDetection and analysis of microbial strain secretions
Integrating trait associations and network topology prioritized two culturable, legacy-linked taxa, Sphingomonas montis and Pseudarthrobacter oxydans, associated with nitrogen uptake and network centrality, respectively, which were assembled into the minimal two-member synthetic community.
2026-05-16 | MTBLS14501 | MetaboLights
MetabolomicsPlasmid-encoded toxin defence mediates mutualistic microbial interactions

Gut environments harbour dense microbial ecosystems in which plasmids are widely distributed. Plasmids facilitate the exchange of genetic material among microorganisms while enabling the transfer of a diverse array of accessory functions. However, their precise impact on microbial community compo...

2023-08-10 | MTBLS7248 | MetaboLights
MetabolomicsInfluence of Culture Conditions on Metabolite Diversity in Epichloë sinensis Strains

Epichloë sinensis, associated with Festuca sinensis, exhibits rich morphological, genetic and functional diversity across different strains. To comprehensively evaluate the categories and difference in the secondary metabolites of different E. sinensis strains and thereby...

2026-01-04 | MTBLS13598 | MetaboLights
MetabolomicsSmall intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders
Small intestinal bacterial overgrowth (SIBO) has been implicated in symptoms associated with functional gastrointestinal disorders (FGIDs), though mechanisms remain poorly defined and treatment involves non-specific antibiotics. Here we show that SIBO based on duodenal aspirate culture reflects an o...
2019-04-30 | MTBLS876 | MetaboLights
MetabolomicsConsistency across multi-omics layers in a drug-perturbed gut microbial community
Multi-omics analyses are increasingly employed in microbiome studies to obtain a holistic view of molecular changes occurring within microbial communities exposed to different conditions. However, it is not always clear to what extent each omics data type contributes to our understanding of the comm...
2022-12-08 | MTBLS3129 | MetaboLights
Genomicsmixed culture metagenome
mixed culture metagenome Metagenome
PRJNA387091 | ENA
Genomicsmixed culture metagenome
mixed culture metagenome Metagenome
PRJNA530831 | ENA
Genomicsmixed culture metagenome
mixed culture metagenome Raw sequence reads
PRJNA352295 | ENA
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