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TranscriptomicsGenome-wide DNA Microarray Unravels Rapid Changes in the Transcriptome of MK-801 treated Rat Brain
Background: N-Methyl-D-aspartate receptors (NMDAr), widely located around the central nervous system, are known to be involved in behavioral disorders. Dizocilpine (commonly referred to as MK-801) is a well known non-competitive NMDAr antagonist. Methods: We treated rats with intraperitoneal injecti...
ORGANISM(S): Rattus norvegicus 
2012-04-24 | E-GEOD-37413 | biostudies-arrayexpress
TranscriptomicsGenome-wide DNA Microarray Analysis Unravels Rapid Changes in the Transcriptome of MK-801 treated Rat Brain
N-Methyl-D-aspartate receptors (NMDAr), widely located around the central nervous system, are known to be involved in behavioral disorders. Dizocilpine (commonly referred to as MK-801) is a well known non-competitive NMDAr antagonist. We treated rats with intraperitoneal injection [0.08 (low-dose) a...
ORGANISM(S): Rattus norvegicus 
2014-11-26 | E-GEOD-63639 | biostudies-arrayexpress
GenomicsRibosome Profiling Reveals MK-801-Induced Differential Translation in the Prefrontal Cortex of Acute MK-801-Exposed Male Mice
Ribosome Profiling Reveals MK-801-Induced Differential Translation in the Prefrontal Cortex of Acute MK-801-Exposed Male Mice
PRJNA576586 | ENA
TranscriptomicsRibosome Profiling Reveals MK-801-Induced Differential Translation in the Prefrontal Cortex of Acute MK-801-Exposed Male Mice
Differential translation significantly contributes to gene expression regulation and FMRP is one of the upstream translation regulators in the PFC of MK-801-exposed juvenile male mice Acute exposure to the NMDA receptor antagonist MK-801 induces schizophrenia-like behavioral endophenotypes in juveni...
ORGANISM(S): Mus musculus 
2026-10-01 | GSE138616 | GEO
GenomicsExpression data from rat prefrontal cortex administrated with MK-801
Expression data from rat prefrontal cortex administrated with MK-801
PRJNA910095 | ENA
TranscriptomicsGenome-wide DNA Microarray Unravels Rapid Changes in the Transcriptome of MK-801 treated Rat Brain
Background: N-Methyl-D-aspartate receptors (NMDAr), widely located around the central nervous system, are known to be involved in behavioral disorders. Dizocilpine (commonly referred to as MK-801) is a well known non-competitive NMDAr antagonist. Methods: We treated rats with intraperitoneal injecti...
ORGANISM(S): Rattus norvegicus 
2012-04-25 | GSE37413 | GEO
TranscriptomicsGenome-wide DNA Microarray Analysis Unravels Rapid Changes in the Transcriptome of MK-801 treated Rat Brain
N-Methyl-D-aspartate receptors (NMDAr), widely located around the central nervous system, are known to be involved in behavioral disorders. Dizocilpine (commonly referred to as MK-801) is a well known non-competitive NMDAr antagonist. We treated rats with intraperitoneal injection [0.08 (low-dose) a...
ORGANISM(S): Rattus norvegicus 
2014-11-26 | GSE63639 | GEO
TranscriptomicsExpression data from rat prefrontal cortex administrated with MK-801
Schizophrenia is a group of severe mental disorders. MK-801 is a common chemical that is used to construct schizophrenic animal model. In the present study, male SD rats were received MK-801 (0.2 mg/kg) intraperitoneal injections for 2 weeks. PFC tissue samples were collected freshly when sacrificin...
ORGANISM(S): Rattus norvegicus 
2023-01-09 | GSE220510 | GEO
GenomicsEffects of the Co-Administration of MK-801 and Clozapine on MiRNA Expression Profiles in Rats
Effects of the Co-Administration of MK-801 and Clozapine on MiRNA Expression Profiles in Rats
PRJNA531444 | ENA
TranscriptomicsEffects of the Co-Administration of MK-801 and Clozapine on MiRNA Expression Profiles in Rats
Background: microRNAs (miRNAs) are small, non-coding RNAs, which can silence the expression of various target genes via binding their mRNAs, thus miRNAs serve and regulate a wide range of crucial functions in the body. However, the miRNAs expression profile after the antipsychotics mediation in schi...
ORGANISM(S): Rattus norvegicus 
2020-10-01 | GSE129466 | GEO
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