Sort   by:  
 Page size 
UnknownMK-8776, a novel chk1 kinase inhibitor, radiosensitizes p53-defective human tumor cells.
Not available
S-EPMC5342109 | biostudies-literature
UnknownChk1 Inhibitor MK-8776 Restores the Sensitivity of Chemotherapeutics in P-glycoprotein Overexpressing Cancer Cells.
Not available
S-EPMC6747525 | biostudies-literature
UnknownMK-8776, a novel Chk1 inhibitor, exhibits an improved radiosensitizing effect compared to UCN-01 by exacerbating radiation-induced aberrant mitosis.
Not available
S-EPMC5447387 | biostudies-literature
UnknownRandomized phase II trial of cytosine arabinoside with and without the CHK1 inhibitor MK-8776 in relapsed and refractory acute myeloid leukemia.
Not available
S-EPMC5639924 | biostudies-literature
UnknownComparative Activity and Off-Target Effects in Cells of the CHK1 Inhibitors MK-8776, SRA737, and LY2606368.
Not available
S-EPMC8033610 | biostudies-literature
GenomicsGene expression profiling of ATRA-resistant NB4-MR4 subclone (R4 cell line) treated with a CHK1 inhibitor i(MK-8776).
Gene expression profiling of ATRA-resistant NB4-MR4 subclone (R4 cell line) treated with a CHK1 inhibitor i(MK-8776).
PRJNA925828 | ENA
UnknownMK-8776 and Olaparib Combination Acts Synergistically in Hepatocellular Carcinoma Cells, Demonstrating Lack of Adverse Effects on Liver Tissues in Ovarian Cancer PDX Model.
Not available
S-EPMC11766115 | biostudies-literature
UnknownA subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase.
Not available
S-EPMC4811467 | biostudies-literature
UnknownInhibition of checkpoint kinase 1 potentiates anticancer activity of gemcitabine in bladder cancer cells.
Not available
S-EPMC8119486 | biostudies-literature
UnknownChk1 inhibition-induced BRCAness synergizes with olaparib in p53-deficient cancer cells.
Not available
S-EPMC9815235 | biostudies-literature
Sort   by:  
 Page size