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Human Exon Array Profiling of Ewing sarcoma

Ewing sarcoma family tumors (ESFTs) are aggressive tumors of putative stem cell origin for which prognostic biomarkers and novel treatments are needed. We have previously shown that the polycomb gene BMI-1 functions as an oncogene in ESFT. In several human cancers, high expression of BMI-1 is associ...

ORGANISM(S): Homo sapiens

2010-06-08 | E-GEOD-16016 | biostudies-arrayexpress

Phase II Single-Arm Study of Preoperative Letrozole for Estrogen Receptor-Positive Postmenopausal Ductal Carcinoma In Situ: CALGB 40903 (Alliance).

Not available

S-EPMC7164489 | biostudies-literature

Global gene expression profiles in Oct4-knockdown and Ccna2-knockdown mouse embryos.

Gene regulation at the maternal-embryonic transition in the pre-implantation mouse embryo is not well understood. We knock down Ccna2 to establish proof-of-concept that antisense morpholino oligonucleotides can be used to target specific genes. We applied this strategy to study Oct4 and discovered...

ORGANISM(S): Mus musculus

2008-12-30 | E-GEOD-13981 | biostudies-arrayexpress

Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women.

Not available

S-EPMC4993693 | biostudies-literature

Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.

Not available

S-EPMC12535840 | biostudies-literature

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Not available

S-EPMC4835977 | biostudies-literature

Global age-sex-specific all-cause mortality and life expectancy estimates for 204 countries and territories and 660 subnational locations, 1950-2023: a demographic analysis for the Global Burden of Disease Study 2023.