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TranscriptomicsDevelopmental gene expression profiles of the human pathogen Schistosoma japonicum
The life cycle of schistosomes is complex, being characterised by a series of distinct parasitic and free-living phases involving an invertebrate snail host, water and a mammalian host. A custom designed oligonucleotide microarray was utilized to profile developmental gene expression in the Asian bl...
ORGANISM(S): Schistosoma japonicum 
2010-06-19 | E-GEOD-12704 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiles of adult Schistosoma japonicum in response to insulin
To define the differential gene regulation of adult Schistosoma japonicum in response to host insulin, we utilised a parasite microarray with 38,444 probes representing 19,222 genes. We cultured male and female adult worms were exposed to insulin and glucose; and then parasites were collected at thr...
ORGANISM(S): Schistosoma japonicum 
2010-06-24 | E-GEOD-13891 | biostudies-arrayexpress
TranscriptomicsTranscriptional changes in the secretome of S. mansoni during early development and in the presence of erythrocytes
We have examined the gene expression profile of the transformation of the blood fluke Schistosoma mansoni from the cercarial to schistosomula stages. Specifically cercariae were mechanically transformed and then cultured for 3 hours or 5 days, and then total RNA was isolated and microarray analysis...
ORGANISM(S): Schistosoma mansoni 
2010-06-21 | E-GEOD-18335 | biostudies-arrayexpress
TranscriptomicsTissue specific profiling of the human pathogen Schistosoma japonicum
Key tissues of the adult female parasite involved in nutritional uptake and reproduction were examined using a novel gene discovery approach that combined laser microdissection microscopy and microarray analyses. Gastrodermis, vitelline glands and ovary were microdissected from unfixed, frozen secti...
ORGANISM(S): Schistosoma japonicum 
2010-06-19 | E-GEOD-12706 | biostudies-arrayexpress
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