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UnknownUsing TLC-MALDI-TOF to Interrogate In Vitro Peptidyl Proximal Preferences of PARP14 and Glycohydrolase Specificity.
Not available
S-EPMC10459978 | biostudies-literature
UnknownIdentification of a Novel PARP14 Site Motif and Glycohydrolase Specificity Using TLC-MALDI-TOF.
Not available
S-EPMC10055325 | biostudies-literature
TranscriptomicsMesothelioma-associated fibroblasts enhance proliferation and migration of malignant pleural mesothelioma cells via Met/PI3K and WNT signaling but do not protect against cisplatin
Malignant pleural mesothelioma (MPM) is an aggressive malignancy with poor prognosis. Unlike many other cancers, MPM is mostly characterized by inactivation of tumor suppressor genes. Its highly malignant nature in absence of tumor driving oncogene mutations indicates an extrinsic supply of stimulat...
ORGANISM(S): Homo sapiens 
2022-12-31 | E-MTAB-12179 | biostudies-arrayexpress
TranscriptomicsHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Impairment of hepatic growth hormone (GH)- janus kinase (JAK) 2- signal transducer and activator of transcription (STAT) 5 signaling is associated with non-alcoholic fatty liver disease, while persistently high levels of GH can result in hepatic inflammation and liver cancer. Despite its anti-steato...
ORGANISM(S): Mus musculus 
2016-10-01 | E-MTAB-3774 | biostudies-arrayexpress
TranscriptomicsRegulation of HB-EGF by miR-212 and acquired cetuximab-resistance in head and neck cancer
To determine the mechanism of cetuximab-resistance in head and neck cancer, a cetuximab-sensitive cell line (SCC1) and its cetuximab-resistant derivative (1Cc8) were analyzed for differentially expressed genes using DNA microarrays. 900 differentially expressed genes were found using the statistical...
ORGANISM(S): Homo sapiens 
2011-01-14 | E-GEOD-21483 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo.
To determine hypoxia mediated changes in whole blood, normal C57Bl/10 mice were gradually exposed to a chronic hypoxic environment, equivalent to an altitude of 6500m, for 2 weeks in vivo. Control, age-matched mice were maintained under normoxic, normobaric conditions by exposing them to ambient air...
ORGANISM(S): Mus musculus 
2010-05-07 | E-GEOD-15894 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression in whole blood of mice subjected to hypobaric hypoxia at Mt. Everest in vivo.
To determine hypoxia mediated changes in whole blood, normal swiss webster mice were gradually exposed to a chronic hypobaric hypoxic environment up to 8500m, for 2 weeks in vivo. Control, age-matched mice were maintained under normoxic conditions in Kathmandu (c. 1300 mts above sea level). Purpose:...
ORGANISM(S): Mus musculus 
2010-05-07 | E-GEOD-15901 | biostudies-arrayexpress
TranscriptomicsEstablishment and Molecular Characterization of Glioblastoma Primary Cultures
Glioblastoma, the most frequent and malignant adult brain tumor has been extensively studied; yet no effective treatment exists. To overcome this dismal scenario, it is essential to improve preclinical biological models. This study aimed to establish and molecularly characterize glioblastoma primary...
ORGANISM(S): Homo sapiens 
2016-07-01 | E-GEOD-59967 | biostudies-arrayexpress
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