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ProteomicsA strategy to characterize the global histone PTM landscape within tissues of non-model organisms
Histone post-translational modifications (PTMs) are epigenetic marks that play a critical role in the expression and maintenance of DNA, but they remain largely uninvestigated in non-model organisms due to technical challenges. To begin alleviating this issue, we developed a workflow for histone PTM...
ORGANISM(S): Oreochromis Mossambicus 
2024-02-29 | PXD040536 | panorama
ProteomicsEnvironmental Conditions Elicit a Slow but Enduring Response of Histone Post-Translational Modifications in Mozambique Tilapia
Histone post-translational modifications (PTMs) are epigenetic marks that operate within the central dogma of molecular biology: upon an environmental stimulus, the histone PTMs surrounding DNA can be changed in a way that modifies gene expression, and, therefore, the abundance and composition of RN...
ORGANISM(S): Oreochromis Mossambicus 
2024-12-10 | PXD042718 | panorama
ProteomicsSalinity-responsive histone PTMs identified in Mozambique tilapia tissues
Histone post-translational modifications (PTMs) are epigenetic marks that can be induced by environmental stress and elicit heritable patterns of gene expression. To investigate this process in an ecological context, we characterized the influence of salinity stress on histone PTMs within the gills,...
ORGANISM(S): Oreochromis Mossambicus 
2024-07-26 | PXD040557 | panorama
ProteomicsGlobal maintenance of histone post-translational modifications during the transition into anoxia in embryos of the annual killifish Austrofundulus limnaeus
Embryos of the annual killifish Austrofundulus limnaeus have the greatest tolerance to anoxia of all vertebrates, making them a powerful model to study the cellular mechanisms necessary for anoxia tolerance. However, the global histone landscape of this species has never been quantified or explored ...
ORGANISM(S): Austrofundulus Limnaeus 
2026-01-23 | PXD058622 | panorama
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