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TranscriptomicsGene expression in mouse hematopoietic stem and multi-potent progenitor cells with temporally defined divisional histories
Homeostatic hematopoietice stem cells (HSCs) with greater divisional history lose repopulating potential after very few cell divisions. Divisional history overrides both phenotype and immediate quiescence in determining functional activity. In GFP label retaining system GFP is progressively diluted ...
ORGANISM(S): Mus musculus 
2014-03-20 | E-GEOD-48261 | biostudies-arrayexpress
TranscriptomicsInduction of a hemogenic program in mouse fibroblasts
Definitive hematopoiesis emerges during embryogenesis via an endothelial-to-hematopoietic transition. We attempted to induce this process in mouse fibroblasts by screening a panel of factors for hemogenic activity. We identified a combination of four transcription factors, Gata2, Gfi1b, cFos, and Et...
ORGANISM(S): Mus musculus 
2013-06-13 | E-GEOD-47497 | biostudies-arrayexpress
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