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TranscriptomicsTranscription profiling of mouse tumors arising in wild-type or St6gal1 null littermates
Sialic acids on vertebrate cell surfaces mediate many biological roles. Altered expression of certain sialic acid types or their linkages can have prognostic significance in human cancer. A classic but unexplained example is enhanced α2-6-sialylation on N-glycans, resulting from over-expression of ...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9447 | biostudies-arrayexpress
GenomicsGenome wide association study of Coeliac Disease
We performed a second-generation genome-wide association study of 4,533 individuals with celiac disease (cases) and 10,750 control subjects. We genotyped 113 selected SNPs with P(GWAS) < 10(-4) and 18 SNPs from 14 known loci in a further 4,918 cases and 5,684 controls. Variants from 13 new regions r...
EGAS00000000057 | EGA
Transcriptomicsp53 amplifies Toll-like receptor 5 response in MCF-7 cells
Using gene expression profiling we characterize the global effect of p53 on the TLR5-mediated transcription in MCF7 cells. We found that combined activation of p53 and TLR5 pathways synergistically increases expression of over 200 genes, mostly associated with immunity and inflammation. The synergy ...
ORGANISM(S): Homo sapiens 
2015-08-26 | E-GEOD-72359 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse glioma cell line grown in two types of media to investigate cell de-differentiation
Comparison of gene expression profiles of the GL261 cell line (a murine glioma model) grown in duplicate in two different types of media. AC samples where grown in DMEM supplemented by 20% FBS, 5 U/ml pen/strep and 4 mM L-glutamine. NS samples were grown in DMEM/F12 (50/50) supplemented with 2 U/ml ...
ORGANISM(S): Mus musculus 
2006-12-31 | E-MEXP-718 | biostudies-arrayexpress
GenomicsFinnuncorrNLITUK1UK3hap300 - samples
All cases and controls (Hap300)
EGAD00010000298 | EGA
GenomicsFinnuncorrNLITUK3hap550_onlyNBS - samples
NBS control samples only (Hap550)
EGAD00010000290 | EGA
GenomicsFinnuncorrNLITUK1UK3hap300_no1958BC_noNBS - samples
All cases and Finnish, Dutch, Italian control samples (Hap300)
EGAD00010000292 | EGA
GenomicsFinnuncorrNLITUK3hap550_only1958BC - samples
1958BC control samples only (Hap550)
EGAD00010000296 | EGA
GenomicsFinnuncorrNLITUK3hap550_no1958BC_noNBS - samples
All cases and Finnish, Dutch, Italian control samples (Hap550)
EGAD00010000288 | EGA
GenomicsFinnuncorrNLITUK1UK3hap300_onlyNBS - samples
NBS control samples only (Hap300)
EGAD00010000284 | EGA
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