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TranscriptomicsImplications of high level pseudogene transcription in Mycobacterium leprae
Approximately half of M. lepraeâ??s transcriptome consists of inactive gene products. This has an impact on overall energy and resource consumption without potential benefit to this organism. However, multiple translational â??silencingâ?? mechanisms are present, reducing additional energy and resou...
ORGANISM(S): Mycobacterium leprae 
2010-06-24 | E-GEOD-17191 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression profiling of leprosy and granuloma annulare skin lesions
Here we report the data generated by short-read sequencing of mRNA (polyA) isolated from granuloma annulare and leprosy skin lesions. Our main aim was to identify putative mRNA biomarkers for distinguishing leprosy from other differential diagnoses. Additionally, we also explored the distinction bet...
ORGANISM(S): Homo sapiens 
2021-10-01 | E-MTAB-10318 | biostudies-arrayexpress
TranscriptomicsEffect of live Mycobacterium leprae infection on global gene expression of primary human Schwann cells at 24 hours
In an attempt to understand M. leprae interaction with the human host, Stanford Genomics HEEBO Arrays were use to identify modulated genes in primary human Schwann cells infected with live M. leprae at a MOI of 100:1 for 24 hours. Dual channel competitive hybridizations between M. leprae infected an...
ORGANISM(S): Homo sapiens 
2013-01-03 | E-GEOD-40950 | biostudies-arrayexpress
TranscriptomicsEffect of live Mycobacterium leprae on primary human Schwann cell gene expression
In attempt to understand M.leprae interaction with the human host, Applied Biosystems microarrays containing 30,865 probles were used to identify modulated genes in primary human Schwann Cells (SC) infected with live M. leprae at two early time points, 24 and 48 hours. A total of 4 independent exper...
ORGANISM(S): Homo sapiens 
2012-06-30 | E-GEOD-35423 | biostudies-arrayexpress
UnknownThe structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding.
Not available
S-EPMC2857111 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
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