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MetabolomicsThe Impacts of Sortase A and the 4'-Phosphopantetheinyl Transferase Homolog Sfp on Streptococcus mutans Extracellular Membrane Vesicle Biogenesis

Extracellular membrane vesicles (EMVs) are produced by many Gram-positive organisms, but information regarding vesiculogenesis is incomplete. We used single gene deletions to evaluate the impacts on Streptococcus mutans EMV biogenesis of Sortase A (SrtA), which affects S. mutans...

2021-10-06 | MTBLS1812 | MetaboLights
ProteomicsBiophysical, proteomic, and lipidomic characterization of Streptococcus mutans extracellular membrane vesicles from wild-type, ΔsrtA, and Δsfp strains provides novel information regarding vesiculogenesis and its function
Extracellular membrane vesicles (EMVs) are produced by many Gram-positive organisms, but information regarding vesiculogenesis is largely unknown. In this study, we isolated and characterized EMVs derived from the oral pathogen Streptococcus mutans and two deletion mutants, ΔsrtA and Δsfp. ΔsrtA E...
ORGANISM(S): Streptococcus mutans serotype C 
2020-11-17 | PXD019825 | Pride
Vesicles Lipidome Proteome Streptococcus mutans Membrane 
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