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GenomicsInsights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis
The transcription factor GATA-1 is required for terminal erythroid maturation and functions as an activator or repressor depending on gene context. Yet its in vivo site selectivity and ability to distinguish between activated versus repressed genes remain incompletely understood. In this study, we p...
ORGANISM(S): Mus musculus 
2009-11-25 | E-GEOD-16594 | biostudies-arrayexpress
GenomicsDirect Recruitment of Polycomb Repressive Complex 1 (PRC1) to Chromatin by Core Binding Transcription Factors (ChIP-Seq)
Polycomb repressive complexes (PRCs) play key roles in developmental epigenetic regulation. Yet the mechanisms that target PRCs to specific loci in mammalian cells remain incompletely understood. In this study, we show that Bmi1, a core component of Polycomb Repressive Complex 1 (PRC1), binds direct...
ORGANISM(S): Mus musculus 
2012-02-10 | E-GEOD-33653 | biostudies-arrayexpress
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S-EPMC10364778 | biostudies-literature
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