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MetabolomicsOxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers
Resistance to endocrine treatments and CDK4/6 inhibitors is considered a near-inevitability in most patients with estrogen receptor positive breast cancers (ER + BC). By genomic and metabolomics analyses of patients' tumours, metastasis-derived patient-derived xenografts (PDX) and isogenic cell line...
2023-06-27 | MTBLS3342 | MetaboLights
TranscriptomicsAginAging: a portrait from gene expression profile in blood cells: a portrait from gene expression profile in blood cells.
In almost every countries the proportion of people over 60 years is growing faster that any other age group. Increased life expectancy is leading to the characterization of specific aspects of aging for the various physiological systems. The study of healthy aging is important to design strategies c...
ORGANISM(S): Homo sapiens 
2016-08-19 | E-GEOD-67220 | biostudies-arrayexpress
UnknownIGF1 and PPARG polymorphisms are associated with reduced estimated glomerular filtration rate in a cohort of children and adolescents with type 1 diabetes.
Not available
S-EPMC10442246 | biostudies-literature
TranscriptomicsGDNF-RET signaling as a target in aromatase inhibitor resistant breast cancers
Understanding the complex molecular mechanisms underlying resistance to endocrine therapy is a major challenge in the treatment of estrogen receptor-positive (ER+) breast cancers. We have previously demonstrated that glial cell line-derived neurotrophic factor (GDNF) signaling via the receptor tyros...
ORGANISM(S): Homo sapiens 
2013-01-17 | E-MEXP-3662 | biostudies-arrayexpress
no omics definedTranscription profiling of camptothecin treatment time series performed on human U87 glioma cells
Time-series analysis of camptothecin effects on U87 glioma cells
ORGANISM(S): Homo sapiens 
2006-09-30 | E-MEXP-741 | biostudies-arrayexpress
UnknownReliability, validity and discriminant ability of the instrumental indices provided by a novel planar robotic device for upper limb rehabilitation.
Not available
S-EPMC5956822 | biostudies-literature
UnknownJugular vs femoral vein for central venous catheterization in pediatric cardiac surgery (PRECiSE): study protocol for a randomized controlled trial.
Not available
S-EPMC6019231 | biostudies-literature
UnknownSarcopenia associates with SNAP-25 SNPs and a miRNAs profile which is modulated by structured rehabilitation treatment.
Not available
S-EPMC8296538 | biostudies-literature
UnknownCell surface Nucleolin represents a novel cellular target for neuroblastoma therapy.
Not available
S-EPMC8170797 | biostudies-literature
UnknownComplete corpus callosum agenesis: can it be mild?
Not available
S-EPMC3437615 | biostudies-literature
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